Tıp Fakültesi

Akademik Kadro

Prof. Dr. Özlem Özdemir Gürsoy

Prof. Dr.
Özlem Özdemir Gürsoy

Nöroloji

Çalışma Alanları

  • Sağlık Bilimleri Temel Alanı
  • Nöroloji
  • Isolated Hypoglossal Nerve Palsy due to a Jugular Foramen Schwannoma, 2019
  • Improving Microcirculatory Reperfusion Reduces Parenchymal Oxygen Radical Formation and Provides Neuroprotection, 2018
  • A MULTIDISCIPLINARY CLINICAL APPROACH TO FACIOSCAPULOHUMERAL MUSCULAR DYSTROPHY ORTHOPEDIC SURGERY IN FACIOSCAPULOHUMERAL DYSTROPHY, 2018
  • A multidisciplinary clinical approach to facioscapulohumeral muscular dystrophy, 2018
  • Microembolism of single cortical arterioles can induce spreading depression and ischemic injury a potential trigger for migraine and related MRI lesions, 2018
  • Inadequate brain glycogen or sleep increases spreading depression susceptibility, 2018
  • Behçet Disease serum is immunoreactive to neurofilament medium which share common epitopes to bacterial HSP-65, a putative trigger, 2017
  • Data of indirect immunofluorescence labeling of the mouse brain sections with sera from SLE and MS patients, 2017
  • Nose-to-brain delivery of farnesylthiosalicylic acid loaded hybrid nanoparticles in the treatment of glioblastoma, 2017
  • A potential non-invasive glioblastoma treatment: Nose-to-brain delivery of farnesylthiosalicylic acid incorporated hybrid nanoparticles, 2017
  • Data of indirect immunofluorescence labeling of the mouse brain sections with sera from SLE and MS patients, 2017
  • Reversible transverse sinus collapse in a patient with idiopathic intracranial hypertension, 2016
  • Systemically administered brain targeted nanoparticles transport peptides across the blood brain barrier and provide neuroprotection, 2014
  • Poloxamer 188 and Citicoline provide neuronal membrane integrity and protect membrane stability in Cortical Spreading Depression, 2014
  • Atypical Aicardi Goutieres Syndrome Is the WRN Locus a Modifier, 2014
  • Nöro Behçet Hastalarının Serumlarında Beyin Dokusu ve Beyin Damarlarına Karşı Otoantikor Varlığı, 2014
  • An aquaporin 4 antisense oligonucleotide loaded brain targeted nanoparticulate system design, 2014
  • Comparative in vitro studies on PBN loaded nanoparticles prepared by biodegradable chitosan PLGA polymers and their PEGylated block copolymers, 2014
  • Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy CADASIL in Two Siblings with Neuropsychiatric Symptoms, 2013
  • Cell death and survival mechanisms are concomitantly active in the hippocampus of patients with mesial temporal sclerosis, 2013
  • Spreading Depression Triggers Headache by Activating Neuronal Panx1 Channels, 2013
  • Plasma 3 nitrotyrosine estimates the reperfusion induced cerebrovascular stress whereas matrix metalloproteinases mainly reflect plasma activity a study in patients treated with thrombolysis or endovascular recanalization, 2012
  • Microvascular protection is essential for successful neuroprotection in stroke, 2012
  • Brain microvascular pericytes in health and disease, 2011
  • Thrombotic distal middle cerebral artery occlusion produced by topical FeCl3 application a novel model suitable for intravital microscopy and thrombolysis studies, 2011
  • Megestrol acetate inhibits the expression of cytoplasmic aromatase through nuclear C EBP in reperfusion injury induced ischemic rat hippocampus, 2011
  • Alpha synuclein aggregation induced by brief ischemia negatively impacts neuronal survival in vivo a study in A30P alpha synuclein transgenic mouse, 2010
  • Lysosomal rupture necroapoptotic interactions and potential crosstalk between cysteine proteases in neurons shortly after focal ischemia, 2010
  • Reply to Pericyte constriction after stroke the jury is still out, 2010
  • Changes in the Expression of Selenoproteins in Mesial Temporal Lobe Epilepsy Patients, 2009
  • A Nanomedicine Transports a Peptide Caspase 3 Inhibitor across the Blood Brain Barrier and Provides Neuroprotection, 2009
  • Astrocytes are More Resistant to Focal Cerebral Ischemia Than Neurons and Die by a Delayed Necrosis, 2009
  • Pericyte contraction induced by oxidative nitrative stress impairs capillary reflow despite successful opening of an occluded cerebral artery, 2009
  • A new model of transient focal cerebral ischemia for inducing selective neuronal necrosis, 2009
  • Hydrogen peroxide induced stroke elucidation of the mechanism in vivo, 2009
  • VEGF protects brain against focal ischemia without increasing blood brain permeability when administered intracerebroventricularly, 2005
  • Apoptotic and Necrotic Death Mechanisms Are Concomitantly Activated in the Same Cell After Cerebral Ischemia, 2004
  • Mouse Model of Microembolic Stroke and Reperfusion, 2004
  • Loss of NeuN immunoreactivity after cerebral ischemia does not indicate neuronal cell loss A cautionary note, 2004
  • Laser Speckle Flowmetry for the Study of Cerebrovascular Physiology in Normal and Ischemic Mouse Cortex, 2004
  • Reperfusion Induced Oxidative Nitrative Injury to Neurovascular Unit After Focal Cerebral Ischemia, 2004
  • Cortical spreading depression activates and upregulates MMP 9, 2004
  • Is the Cell Death in Mesial Temporal Sclerosis Apoptotic, 2003
  • Persistent Defect in Transmitter Release and Synapsin Phosphorylation in Cerebral Cortex After Transient Moderate Ischemic Injury, 2002
  • Spleen damage in endotoxaemic mice the involvement of nitric oxide, 2001
  • Chronic daily administration of selegiline and EGb 761 increases brain s resistance to ischemia in mice, 2001
  • Altered mechanisms of motor evoked potential generation after transient focal cerebral ischemia in the rat implications for transcranial magnetic stimulation, 2000
  • Role of endothelial nitric oxide generation and peroxynitrite formation in reperfusion injury after focal cerebral ischemia, 2000
  • Pinealectomy aggravates and melatonin administration attenuates brain damage in focal ischemia, 1999
  • Occlusion of the MCA by an intraluminal filament may cause disturbances in the hippocampal blood flow due to anomalies of circle of Willis and filament thickness, 1999
  • Multiple Skleroz Patofizyolojisinde Perisitlerin Rolü,
  • A Novel Shoulder Disability Staging System For Scapulothoracic Arthrodesis In Patients With Facioscapulohumeral Dystrophy, 2017
  • The effect of coating materials on morphology and function of the cells in two and three-dimensional primary neuronal cultures,
  • THE BIODISTRIBUTION OF FARNESYLTHIOSALICYLIC ACIDINCORPORATED HYBRID NANOPARTICLES FOLLOWINGINTRANASAL ADMINISTRATION IN RATS, 2017
  • Nanotechnology Methods for Neurological Diseases and Brain Tumor, ISBN: 9780128037966, 2017
  • Geriatri ve Gerontoloji, ISBN: , 2006
  • İç Hastalıkları, ISBN: , 2008
  • Akut İskemik İnme, ISBN: , 2001
  • Methods in Enzimology NANOMEDICINE CANCER DIABETES AND CARDIOVASCULAR CENTRAL NERVOUS SYSTEM PULMONARY AND INFLAMMATORY DISEASES, ISBN: 978-0-12-391860-4, 2012
  • Bilim Teşvik Ödülü, 2008
  • Bilim Teşvik Ödülü, 2008
  • Aysun Temizel Bilim Teşvik Ödülü, 2007
  • Bilim Teşvik Ödülü, 2006
  • Genç. Bilim İnsanı Destekleme Programı, 2005
  • International Fellowship Award, 2001
  • Postdoctoral fellowship award, 2000
  • Travel Grant, 1999
  • Kimya Yarışması İkincilik Ödülü, 1985
  • Bilim Adamı Yetiştirme Bursu, 1982