Faculty of Medicine

Faculty of Medicine

Academic Members

Engin Ulukaya

Engin Ulukaya,  Prof.

eulukaya@istinye.edu.tr
CV
Faculty Member

Professor Dr. Engin Ulukaya, after graduating from Istanbul University Cerrahpaşa Medical Faculty in 1987, completed his Medical Biochemistry specialization at Uludağ University. He completed his doctorate (PhD) at the University of Leeds (UK), School of Biochemistry and Molecular Biology. He is working on basic cancer research, cell death, cancer drug development, and personal oncology. In addition to being the chair of the Molecular Cancer Research Association (MOKAD), he is a member of the Council in EACR (European Association for Cancer Research) and a full member of the EORTC PathoBiology subgroup. He has published 137 articles in international journals (Google Scholar H index: 32, Number of citations: 3385). He received the “promising laboratory physician” award at the world pathology and laboratory medicine association (WASPALM) congress held in South Korea in 2003 and was awarded the WASPALM medal. He also has 32 awards in various categories, 3 of which are abroad. He is the Dean of Health Sciences at Istinye University. He is also the Director of the Molecular Cancer Application and Research Center (ISUMKAM) of the same university.

Research Areas: Anticancer Drug Development, Cancer Stem Cell, Personalized Oncology, Cell Death

Main Areas: Tıbbi Biyokimya, 

2022 - The improved killing of both androgen-dependent and independent prostate cancer cells by etoposide loaded SPIONs coupled with NIR irradiation
ONBAŞLI KÜBRA, erkısa merve, DEMİRCİ GÖKTUĞ, muti a, ULUKAYA ENGİN, a sennaroğlu, YAĞCI ACAR HAVVA. BIOMATERIALS SCIENCE, 10(14), 3951-3962.
2022 - Evidence for heterogeneity in response to treatment in mammary tumors of dogs as happens in humans
TURNA ÖZGE, ÜVEZ AYÇA, BAYKAL ASLIHAN, develi elif sedef, dramali murat, SÖNMEZ KIVILCIM, KARAKAŞ ZEYBEK DİDEM, KAŞIKÇI GÜVEN, ARMUTAK ELİF İLKAY, ULUKAYA ENGİN. VETERINARY RESEARCH COMMUNICATIONS,
2022 - Differential of cholangiocarcinoma disease using Raman spectroscopy combined with multivariate analysis
Depciuch Joanna, Parlinska-Wojtan, Magdalena, SERİN KÜRŞAT RAHMİ, BULUT HURİ, TARHAN KAŞİF NEVZAT, GÜLEKEN ZOZAN. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 272(),
2022 - Development of a cysteine responsive chlorinated hemicyanine for image-guided dual phototherapy
savani samira, ONBAŞLI KÜBRA, GÜNDÜZ HANDE, Aydındoğan Eda, ERKISA MERVE, Muti Abdullah, Khan Mihail, SENNAROĞLU ALPHAN, ULUKAYA ENGİN, YAĞCI ACAR HAVVA, koleman safacan. BIOORGANIC CHEMISTRY, 122(),
2022 - DNA Damage Response Inhibitors in Cholangiocarcinoma: Current Progress and Perspectives
GÖNÜL GEYİK ÖYKÜ, Anichini, Guilia, ULUKAYA ENGİN, Marra Fabio, Raggi Chiara. CELLS, 11(9),
2022 - Synthesis, DNA Binding and Cytotoxic Activity of Newcopper(II) Complexes of Trisubstituted Imidazoles
GERÇEK ZUHAL, YILDIZ UFUK, ULUKAYA ENGİN, AKAR REMZİ OKAN. PHARMACEUTICAL CHEMISTRY JOURNAL, 55(12), 1320-1328.
2022 - Novel 5-fluorouracil complexes of Zn(II) with pyridine-based ligands as potential anticancer agents
İÇSEL YILMAZ CEYDA, YILMAZ VEYSEL TURAN, AYGÜN MUHİTTİN, ERKISA MERVE, ULUKAYA ENGİN. DALTON TRANSACTIONS, 51(13), 5208-5217.
2022 - Pyruvate Dehydrogenase Contributes to Drug Resistance of Lung Cancer Cells Through Epithelial Mesenchymal Transition
CEVATEMRE BUSE, ULUKAYA ENGİN, DERE EGEMEN, DİLEGE MUSTAFA ŞÜKRÜ, AÇILAN AYHAN CEYDA. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 9(),
2022 - Natural Products as a Promising Therapeutic Strategy to Target Cancer Stem Cells
ERKISA MERVE, sarıman melda, GÖNÜL GEYİK ÖYKÜ, GEYİK CANER, Stajoykovic Tatjana, ULUKAYA ENGİN. CURRENT MEDICINAL CHEMISTRY, 29(4), 741-783.
2022 - Effects of Exosomes on Major Pathways Promote Tumor Formation and Progression
köse mehmet emin, aydın beste, GEYİK CANER, GÖNÜL GEYİK ÖYKÜ, ULUKAYA ENGİN. CURRENT MOLECULAR MEDICINE, 22(6), 491-505.
2021 - Preparation and Characterization of Palladium Derivate-Loaded Micelle Formulation in Vitro as an Innovative Therapy Option against Non-Small Cell Lung Cancer Cells
ERKISA MERVE, ARI FERDA, BÜYÜKKÖROĞLU GÜLAY, ŞENEL BEHİYE, YILMAZ VEYSEL TURAN, ULUKAYA ENGİN. CHEMISTRY & BIODIVERSITY, 18(9),
2021 - Palladium (II) complex and thalidomide intercept angiogenic signaling via targeting FAK/Src and Erk/Akt/PLC gamma dependent autophagy pathways in human umbilical vein endothelial cells
Aydınlık Şeyma, ÜVEZ AYÇA, KIYAN HÜLYA TUBA, GÜREL GÜREVİN EBRU, YILMAZ VEYSEL TURAN, ULUKAYA ENGİN, ARMUTAK ELİF İLKAY. MICROVASCULAR RESEARCH, 138(),
2021 - Anticancer Potential of Albumin Bound Wnt/beta-Catenin Pathway Inhibitor Niclosamide in Breast Cancer Cells
ARI FERDA, erkısa merve, pekel gonca, ERTÜRK ELİF, BÜYÜKKÖROĞLU GÜLAY, ULUKAYA ENGİN. CHEMISTRYSELECT, 6(29), 7463-7475.
2021 - Water-soluble silver(I) complexes with N-donor benzimidazole ligands containing an imidazolium core: stability and preliminary biological studies
KARAKAŞ ZEYBEK DİDEM, ÖZDEMİR NAMIK, sarıman melda, GÜNAL SELAMİ, ULUKAYA ENGİN, ÖZDEMİR İSMAİL. DALTON TRANSACTIONS, 50(33), 11596-11603.
2021 - Tumor Chemosensitivity Assays Are Helpful for Personalized Cytotoxic Treatments in Cancer Patients
ULUKAYA ENGİN, Dimas Konstantinos, KARAKAŞ ZEYBEK DİDEM. MEDICINA-LITHUANIA, 57(6),
2021 - Epigenetic modulators combination with chemotherapy in breast cancer cells
ARI FERDA, Napieralski Rudolph, akgün oğuz, Magdolen Viktor, ULUKAYA ENGİN. CELL BIOCHEMISTRY AND FUNCTION, 39(4), 571-583.
2021 - Soloxolone methyl, as a 18 beta H-glycyrrhetinic acid derivate, may result in endoplasmic reticulum stress to induce apoptosis in breast cancer cells
Alper Pınar, salomatina oksana, Salakhutdinov Nariman, ULUKAYA ENGİN, ARI FERDA. BIOORGANIC & MEDICINAL CHEMISTRY, 30(),
2021 - Palladium (II) Complex Enhances ROS-Dependent Apoptotic Effects via Autophagy Inhibition and Disruption of Multiple Signaling Pathways in Colorectal Cancer Cells
Aydınlık Şeyma, ERKISA MERVE, ARI FERDA, ÇELİKLER KASIMOĞULLARI SERAP, ULUKAYA ENGİN. ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 21(6), 1284-1291.
2021 - Combination of Histone Deacetylase Inhibitor with Cu(II) 5,5-diethylbarbiturate Complex Induces Apoptosis in Breast Cancer Stem Cells: A Promising Novel Approach
ERKISA MERVE, AZTOPAL NAZLIHAN, ERTÜRK ELİF, ULUKAYA ENGİN, YILMAZ VEYSEL TURAN, ARI FERDA. ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 21(14), 1850-1860.
2021 - Investigation of the efficacy of paclitaxel on some miRNAs profiles in breast cancer stem cells
ERTÜRK ELİF, ARI FERDA, akgün oğuzhan, ULUKAYA ENGİN, küçükali ismail cem, ZEYBEK ŞAKİR ÜMİT. TURKISH JOURNAL OF BIOLOGY, 45(5), 613-.
2021 - Lichens exerts an anti-proliferative effect on human breast and lung cancer cells through induction of apoptosis
ÖZTÜRK ŞULE,Erkısa Merve,ORAN SEYHAN,ULUKAYA ENGİN,ÇELİKLER KASIMOĞULLARI SERAP,ARI FERDA. DRUG AND CHEMICAL TOXICOLOGY, 44(3), 259-267.
2020 - Etoposide Loaded SPION-PNIPAM Nanoparticles Improve thein vitroTherapeutic Outcome on Metastatic Prostate Cancer Cells via Enhanced Apoptosis
ERKISA MERVE, ARI FERDA, irem ülkü, KHODADUST ROUHOLLAH, yar yasemin, YAĞCI ACAR HAVVA, ULUKAYA ENGİN. CHEMISTRY & BIODIVERSITY, 17(11),
2020 - A promising therapeutic combination for metastatic prostate cancer: Chloroquine as autophagy inhibitor and palladium(II) barbiturate complex
erkısa merve, aydınlık şeyma, CEVATEMRE BUSE, AZTOPAL NAZLIHAN, AKAR REMZİ OKAN, ARI FERDA, ÇELİKLER KASIMOĞULLARI SERAP, YILMAZ VEYSEL TURAN, ULUKAYA ENGİN. BIOCHIMIE, 175(), 159-172.
2020 - Protoflavone-Chalcone Hybrids Exhibit Enhanced Antitumor Action through Modulating Redox Balance, Depolarizing the Mitochondrial Membrane, and Inhibiting ATR-Dependent Signaling
ahmed dhahir latif, ULUKAYA ENGİN. Antioxidants, 9(6),
2020 - Trans-Pd/Pt(II) saccharinate complexes with a phosphine ligand: Synthesis, cytotoxicity and structure-activity relationship
İÇSEL YILMAZ CEYDA, YILMAZ VEYSEL TURAN, AYGÜN MUHİTTİN, ULUKAYA ENGİN. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 30(9),
2020 - Toxicity assessment of Hypericum olympicum subsp. olympicum L. on human lymphocytes and breast cancer cell lines
balıkçı necmiye, SARIMAHMUT MEHMET, ARI FERDA, AZTOPAL NAZLIHAN, ÖZEL MUSTAFA ZAFER, ULUKAYA ENGİN, ÇELİKLER KASIMOĞULLARI SERAP. JOURNAL OF APPLIED BIOMEDICINE, 18(1), 18-25.
2020 - Cytotoxic platinum(II) complexes derived from saccharinate and phosphine ligands: synthesis, structures, DNA cleavage, and oxidative stress-induced apoptosis
İÇSEL YILMAZ CEYDA, YILMAZ VEYSEL TURAN, CEVATEMRE BUSE, AYGÜN MUHİTTİN, ULUKAYA ENGİN. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 25(1), 75-87.
2020 - Highly Promising Antitumor Agent of a Novel Platinum(II) Complex Bearing a Tetradentate Chelating Ligand
YILMAZ İSMAİL, AKAR REMZİ OKAN, erkısa merve, selvi selin, selvi selin, ŞENGÜL ABDURRAHMAN, ULUKAYA ENGİN. ACS MEDICINAL CHEMISTRY LETTERS, 11(5), 940-948.
2020 - Mixed ligand complexes of Co(II), Ni(II) and Cu(II) with quercetin and diimine ligands: synthesis, characterization, anti-cancer and anti-oxidant activity
MUTLU GENÇKAL HASENE,Erkisa Merve,Alper Pinar,ŞAHİN SALİHA,ULUKAYA ENGİN,ARI FERDA. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 25(1), 161-177.
2019 - Lichens exerts on anti - proliferative effect on human breast and lung cancer cells through induction of apoptosis
ÖZTÜRK ŞULE,ERKISA MERVE,ORAN SEYHAN,ULUKAYA ENGİN,ÇELİKLER KASIMOĞULLARI SERAP,ARI FERDA. DRUG AND CHEMICAL TOXICOLOGY, 1-9.
2019 - Cytotoxic and genotoxic effects of an endemic plant of Turkey Salvia kronenburgii on breast cancer cell lines
ÇEBİ AYŞEGÜL,AKGÜN EGEMEN,ÇELİKLER KASIMOĞULLARI SERAP,Özel MustafaZafer,ULUKAYA ENGİN,ARI FERDA. Journal of Cancer Research and Therapeutics, 15(5), 1080-.
2019 - Synthesis, characterization, anticancer and antioxidant activity of new nickel(II) and copper(II) flavonoid complexes
Pınar Alper,Erkısa Merve,Genckal Hasene Mutlu,ŞAHİN SALİHA,ULUKAYA ENGİN,ARI FERDA. Journal of Molecular Structure, 1196(), 783-792.
2019 - Structures and anticancer activity of chlorido platinum(II) saccharinate complexes with mono- and dialkylphenylphosphines
İÇSEL CEYDA,YILMAZ VEYSEL TURAN,CEVATEMRE BUSE,AYGÜN MUHİTTİN,ULUKAYA ENGİN. JOURNAL OF INORGANIC BIOCHEMISTRY, 195(), 39-50.
2019 - Cytotoxic and genotoxic effects of an endemic plant of Turkey Salvia kronenburgii on breast cancer cell lines
ÇEBİ AYŞEGÜL,AKGÜN EGEMEN,ÇELİKLER KASIMOĞULLARI SERAP,FIRAT MEHMET,Özel MustafaZafer,ULUKAYA ENGİN,ARI FERDA. Journal of Cancer Research and Therapeutics, 0(0), 0-.
2019 - Unfolded Protein Response is Involved in Trans-Platinum (II) Complex-Induced Apoptosis in Prostate Cancer Cells via ROS Accumulation
KARAKAŞ DİDEM,CEVATEMRE BUSE,YILMAZTEPE ORAL ARZU,YILMAZ VEYSEL TURAN,ULUKAYA ENGİN. Anti-Cancer Agents in Medicinal Chemistry, 19(9), 1184-1195.
2019 - Synthesis and investigation of cytotoxicity of New N- and S,S-substituted-1,4-Naphthoquinone (NQ) Derivatives on Selected Cancer Lines
GÖKMEN ZELİHA,ONAN MEHMET ERDİ,DENİZ NAHİDE GÜLŞAH,KARAKAŞ DİDEM,ULUKAYA ENGİN. SYNTHETIC COMMUNICATIONS,
2019 - A Novel 1,4-Naphtoquinone-Derived Compound Induces Mitochondria-Mediated Apoptotic Cell Death in Breast Cancer Cells
KARAKAŞ DİDEM,AKAR REMZİ OKAN,GÖKMEN ZELİHA,DENİZ NAHİDE GÜLŞAH,ULUKAYA ENGİN. TURKISH JOURNAL OF BIOLOGY,
2019 - Development of near-infrared region luminescent N-acetyl-L cysteine-coated AgS quantum dots with differential therapeutic effect
Buz Pelin Turhan,Duman Fatma Demir,Erkisa Merve,Demirci Gozde,ARI FERDA,ULUKAYA ENGİN,Acar Havva Yagci. Nanomedicine, 14(8), 969-987.
2018 - Structural studies and cytotoxic activity of a new dinuclear coordination compound of palladium(II)-2,2\u2032:6\u2032,2\u2033-terpyridine with rigid dianionic 1,2,4-triazole-3-sulfonate linker
Işık Büyükekşi Sebile,Erkısa Merve,ŞENGÜL ABDURRAHMAN,ULUKAYA ENGİN,YILMAZTEPE ORAL ARZU. APPLIED ORGANOMETALLIC CHEMISTRY, 32(8), 4406-.
2018 - Valproic acid, a histone deacetylase inhibitor, induces apoptosis in breast cancer stem cells.
AZTOPAL NAZLIHAN,ERKISA MERVE,ERTÜRK ELİF,ULUKAYA ENGİN,TOKULLUGİL ASUMAN,ARI FERDA. CHEMICO-BIOLOGICAL INTERACTIONS,
2018 - Quantification of DNA damage products by gas chromatography tandem mass spectrometry in lung cell lines and prevention effect of thyme antioxidants on oxidative induced DNA damage
AYBASTIER ÖNDER,Dawbaa Sam,DEMİR CEVDET,AKGÜN Oğuzhan,ULUKAYA ENGİN,ARI FERDA. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 808(), 1-9.
2018 - An Investigation of Anticancer Effects of Doxorubicin and Calcitriol Combination on MCF-7 Cells
bildiren özge,cevatemre buse,AY EBRU NUR,özen güneş,HEPOKUR CEYLAN,erkısa merve,KÜÇÜKHÜSEYİN ÖZLEM,ULUKAYA ENGİN,KURUCA DÜRDANE SERAP,YAYLIM İLHAN. Experimed, 41-46.
2018 - Synthesis, structures and anticancer potentials of platinum(II) saccharinate complexes of tertiary phosphines with phenyl and cyclohexyl groups targeting mitochondria and DNA
YILMAZ VEYSEL TURAN,İÇSEL CEYDA,Turgut Ömer R,AYGÜN MUHİTTİN,Erkısa Merve,TÜRKDEMİR MEHMET HALUK,ULUKAYA ENGİN. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 155(null), 609-622.
2018 - An Investigation of Anticancer Effects of Doxorubicin and Calcitriol Combination on MCF-7 Cells
Bildiren Ozge,Cevatemre Buse,AY EBRU NUR,Ozen Gunes,HEPOKUR CEYLAN,Erkisa Merve,KÜÇÜKHÜSEYİN ÖZLEM,ULUKAYA ENGİN,KURUCA DÜRDANE SERAP,YAYLIM İLHAN. Experimed, 41-46.
2018 - Chloroquine Used in Combination with Chemotherapy Synergistically Suppresses Growth and Angiogenesis In Vitro and In Vivo
GÜREL GÜREVİN EBRU,KIYAN HULYA TUBA,ESENER OSMAN BEHZAT BURAK,AYDINLIK SEYMA,ÜVEZ AYÇA,ULUKAYA ENGİN,DIMAS KONSTANTINOS,ARMUTAK ELİF İLKAY. Anticancer Research, 38(7), 4011-4020.
2018 - Valproic acid, a histone deacetylase inhibitor, induces apoptosis in breast cancer stem cells.
AZTOPAL NAZLIHAN,ERKISA MERVE,ERTÜRK ELİF,ULUKAYA ENGİN,TOKULLUGİL ASUMAN,ARI FERDA. CHEMICO-BIOLOGICAL INTERACTIONS,
2018 - Usnea filipendula Induces Apoptosis in Human ColonCancer Cell Lines
Disoma Cyrollah,Erkısa Merve,ORAN SEYHAN,Alioğlu İmren,ULUKAYA ENGİN,ARI FERDA. Indian Journal of Pharmaceutical Sciences 1078, 80(6), 1078-1085.
2018 - Pd(II) and Pt(II) saccharinate complexes of bis(diphenylphosphino)propane/butane: Synthesis, structure, antiproliferative activity and mechanism of action
YILMAZ VEYSEL TURAN,İÇSEL CEYDA,AYGÜN MUHİTTİN,ERKISA MERVE,ULUKAYA ENGİN. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 158(), 534-547.
2018 - Synthesis, structures and anticancer potentials of platinum(II) saccharinate complexes of tertiary phosphines with phenyl and cyclohexyl groups targeting mitochondria and DNA
YILMAZ VEYSEL TURAN,İÇSEL CEYDA,TURGUT ÖMER RECEP,AYGÜN MUHİTTİN,ERKISA MERVE,TÜRKDEMİR MEHMET HALUK,ULUKAYA ENGİN. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 155(), 609-622.
2018 - Palladium(ii) and platinum(ii) saccharinate complexes with bis(diphenylphosphino)methane/ethane: synthesis, S-phase arrest and ROS-mediated apoptosis in human colon cancer cells
İÇSEL CEYDA,YILMAZ VEYSEL TURAN,AYGÜN MUHİTTİN,CEVATEMRE BUSE,PINAR ALPER,ULUKAYA ENGİN. Dalton Transactions, 47(33), 11397-11410.
2018 - Palladium(II) and platinum(II) saccharinate complexes with bis(diphenylphosphino)methane/ethane: synthesis, S-phase arrest and ROS-mediated apoptosis in human colon cancer cells
Icsel Ceyda,Yilmaz Veysel Turhan,AYGÜN MUHİTTİN,Cevatemre Buse,Alper Pinar,ULUKAYA ENGİN. Dalton Transactions, 47(33), 11397-11410.
2018 - Synthesis, structures and anticancer potentials of platinum(II) saccharinate complexes of tertiary phosphines with phenyl and cyclohexyl groups targeting mitochondria and DNA
Yilmaz Veysel T.,Icsel Ceyda,Turgut Omer R.,AYGÜN MUHİTTİN,Erkisa Merve,Turkdemir Mehmet H.,ULUKAYA ENGİN. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 155(null), 609-622.
2018 - Usnea filipendula Induces Apoptosis in Human Colon Cancer Cell Lines.
DISOMA CYHROALH,ERKISA MERVE,ORAN SEYHAN,ALOGLOU IMREN,ULUKAYA ENGİN,ARI FERDA. INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 80(6), 1078-1085.
2018 - CHLOROQUINE USED COMBINATION WITH CHEMOTHERAPY SYNERGISTICALLY SUPRESSES GROWTH AND ANGIOGENESIS IN VITRO AND IN VIVO
GÜREL GÜREVİN EBRU,KIYAN HÜLYA TUBA,ESENER OSMAN BEHZAT BURAK,AYDINLIK ŞEYMA,UVEZ AYÇA,ULUKAYA ENGİN,KONSTANTINOS DIMAS,ARMUTAK ELİF İLKAY. ANTICANCER RESEARCH,
2018 - A promising natural product, pristimerin, results in cytotoxicity against breast cancer stem cells in vitro and xenografts in vivo through apoptosis and an incomplete autopaghy in breast cancer
CEVATEMRE BUSE,ERKISA MERVE,AZTOPAL NAZLIHAN,KARAKAŞ DİDEM,Alper Pinar,Tsimplouli Chrisiida,Sereti Evangelia,Dimas Konstantinos,ARMUTAK ELİF İLKAY,GÜREL GÜREVİN EBRU,ÜVEZ AYÇA,Mori Mattia,Berardozzi Simone,Ingallina Cinzia,D’xxAcquarica Ilaria,Botta Bruno,Ozpolat Bulent,ULUKAYA ENGİN. PHARMACOLOGICAL RESEARCH, 129(null), 500-514.
2018 - A promising natural product, pristimerin, results in cytotoxicity against breast cancer stem cells in vitro and xenografts in vivo through apoptosis and an incomplete autopaghy in breast cancer
Cevatemre B,ERKISA MERVE,Aztopal N,KARAKAŞ DİDEM,Alper P,Tsimplouli Chrisiida,Dimas K,Sereti Evangelia,ARMUTAK ELİF İLKAY,GÜREL GÜREVİN EBRU,ÜVEZ AYÇA,Mori Mattia,Berardozzi Simone,Ingallina Cinzia,DAcquarica Ilaria,Botta Bruno,Ozpolat Bulent,ULUKAYA ENGİN. Pharmacological Research,
2018 - Quantification of DNA damage products by gas chromatography tandem mass spectrometry in lung cell lines and prevention effect of thyme antioxidants on oxidative induced DNA damage.
AYBASTIER ÖNDER,Dawbaa Sam,Demir Cevdet,Akgün Oğuzhan,ULUKAYA ENGİN,ARI FERDA. Mutation Research, 808(), 1-9.
2018 - Valproic acid, a histone deacetylase inhibitor, induces apoptosis in breast cancer stem cells
AZTOPAL NAZLIHAN,Erkisa Merve,ERTÜRK ELİF,ULUKAYA ENGİN,TOKULLUGİL HATİCE ASUMAN,ARI FERDA. CHEMICO-BIOLOGICAL INTERACTIONS, 280(), 51-58.
2018 - A PROMISING NATURAL PRODUCT PRISTIMERIN RESULTS IN CYTOTOXICITY AGAINST BREAST CANCER STEM CELLS IN VITRO AND XENOGRAFTS IN VIVO THROUGH APOPTOSIS AN INCOMPLETE AUTHOPHAGY IN BREAST CANCER
CEVATEMRE BUSE,ERKISA MERVE,AZTOPAL NAZLIHAN,KARAKAŞ DİDEM,PINAR ALPER,TSIMPLOULI CHRİSİİDA,SERETI EVANGELIA,KONSTANTINOS DIMAS,ARMUTAK ELİF İLKAY,GÜREL GÜREVİN EBRU,UVEZ AYÇA,MORI MATTIA,BERARDOZZI SIMONE,INGALLINA CINZIA,D ACQUARICA ILARIA,BOTTO BRUNO,OZPOLAT BULENT,ULUKAYA ENGİN. PHARMACOLOGICAL RESEARCH,
2017 - Combination of esomeprazole with chemotherapeutics results in more pronounced cytotoxic effect via apoptosis on A549 nonsmall-cell lung cancer cell line
YILMAZTEPE ORAL ARZU, ORAL HALUK BARBAROS, SARIMAHMUT MEHMET, CEVATEMRE BUSE, ÖZKAYA GÜVEN, KORKMAZ ŞENİZ, ULUKAYA ENGİN. TURKISH JOURNAL OF BIOLOGY, 41(), 231-241.
2017 - Novel 1-(7-ethoxy-1-benzofuran-2-yl) substituted chalcone derivatives: Synthesis, characterization and anticancer activity
COŞKUN DEMET,Erkisa Merve,ULUKAYA ENGİN,COŞKUN MEHMET FATİH,ARI FERDA. European Journal of Medicinal Chemistry, 136(), 212-222.
2017 - A trans-platinum(II) complex induces apoptosis in cancer stem cells of breast cancer
AZTOPAL NAZLIHAN,KARAKAŞ DİDEM,CEVATEMRE BUSE,ARI FERDA,İÇSEL CEYDA,Daidone Maria,ULUKAYA ENGİN. Bioorganic & Medicinal Chemistry, 25(1), 269-276.
2017 - Novel 1-(7-ethoxy-1-benzofuran-2-yl) substituted chalcone derivatives: Synthesis, characterization and anticancer activity
COŞKUN DEMET,erkısa merve,ULUKAYA ENGİN,COŞKUN MEHMET FATİH,ARI FERDA. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 136(), 212-222.
2017 - title Folic acid-conjugated cationic Ag sub2/sub S quantum dots for optical imaging and selective doxorubicin delivery to HeLa cells/title
Duman Fatma Demir,Erkisa Merve,KHODADUST ROUHOLLAH,Ferda Ari,ULUKAYA ENGİN,YAĞCI ACAR HAVVA. Nanomedicine, 12(19), 2319-2333.
2017 - Anti-angiogenic effect of a Palladium(II)-Saccharinate Complex of Terpyridine in vitro and in vivo
ARMUTAK ELİF İLKAY,GÜREL GÜREVİN EBRU,KIYAN HÜLYA TUBA,AYDINLIK ŞEYMA,YILMAZ VEYSEL TURAN,Dimas Konstantinos,ULUKAYA ENGİN. MICROVASCULAR RESEARCH, 109(null), 26-33.
2017 - Folic acid-conjugated cationic Ag2S quantum dots for optical imaging and selective doxorubicin delivery to HeLa cells
DEMİR DUMAN FATMA,Erkısa Merve,Khodadust Rouhollah,ARI FERDA,ULUKAYA ENGİN,YAĞCI ACAR HAVVA. NANOMEDICINE, 12(19), 2319-2333.
2017 - Enhanced cytotoxic activity of doxorubicin through the inhibition of autophagy in triple negative breast cancer cell line
AYDINLIK ŞEYMA,ERKISA MERVE,CEVATEMRE BUSE,SARIMAHMUT MEHMET,DERE EGEMEN,ARI FERDA,ULUKAYA ENGİN. Biochimica et Biophysica Acta (BBA) - General Subjects, 1861(2), 49-57.
2017 - Cytotoxic and apoptotic effects of the combination of palladium (II) 5,5-diethylbarbiturate complex with bis(2-pyridylmethyl)amine and curcumin on non small lung cancer cell lines
TUNÇ DUYGU,DERE EGEMEN,KARAKAŞ DİDEM,CEVATEMRE BUSE,YILMAZ VEYSEL TURAN,ULUKAYA ENGİN. Bioorganic Medicinal Chemistry, 25(5), 1717-1723.
2017 - A trans platinum II complex induces apoptosis in cancer stem cells of breast cancer
Nazlihan Aztopal,Karakaş Didem,CEVATEMRE BUSE,ARI FERDA,İçsel Ceyda,Maria G Maria G Daidone,ULUKAYA ENGİN. Bioorganic Medicinal Chemistry, 25(1), 269-276.
2017 - Nonapoptotic cell death induced by Hypericum species on cancer cells
ARI FERDA,AZTOPAL NAZLIHAN,ERKISA MERVE,ÇELİKLER KASIMOĞULLARI SERAP,ŞAHİN SALİHA,ULUKAYA ENGİN. The European Research Journal, 3(1), 1-10.
2017 - Nonapoptotic cell death induced by Hypericum species on cancer cells
ARI FERDA,aztopal nazlıhan,erkısa merve,ÇELİKLER KASIMOĞULLARI SERAP,ULUKAYA ENGİN. The European Research Journal,
2017 - Nonapoptotic cell death induced by Hypericum species oncancer cells
ARI FERDA,AZTOPAL NAZLIHAN,erkısa merve,ÇELİKLER KASIMOĞULLARI SERAP,ŞAHİN SALİHA,ULUKAYA ENGİN. The European Research Journal, 3(1), 1-10.
2017 - Combination of esomeprazole with chemotherapeutics results in more pronounced cytotoxic effect via apoptosis on A549 nonsmall-cell lung cancer cell line
YILMAZTEPE ORAL ARZU,ORAL HALUK BARBAROS,Sarımahmut Mehmet,CEVATEMRE BUSE,Özkaya G,Şeniz Korkmaz,ULUKAYA ENGİN. TURKISH JOURNAL OF BIOLOGY,
2017 - Enhanced cytotoxic activity of doxorubicin through the inhibition of autophagy in triple negative breast cancer cell line
Aydınlık Şeyma,Erkısa Merve,CEVATEMRE BUSE,Sarımahmut Mehmet,DERE EGEMEN,ARI FERDA,ULUKAYA ENGİN. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS,
2017 - Cytotoxic and apoptotic effects of the combination of palladium (II) 5,5-diethylbarbiturate complex with bis(2-pyridylmethyl)amine and curcumin on non small lung cancer cell lines
Tunç Duygu,DERE EGEMEN,KARAKAŞ DİDEM,CEVATEMRE BUSE,YILMAZ VEYSEL TURAN,ULUKAYA ENGİN. BIOORGANIC MEDICINAL CHEMISTRY,
2017 - Synthesis, structures, DNA/protein binding, molecular docking, anticancer activity and ROS generation of Ni(II), Cu(II) and Zn(II) 5,5-diethylbarbiturate complexes with bis(2-pyridylmethyl) amine and terpyridine
YILMAZ VEYSEL TURAN,İÇSEL CEYDA,Suyunova Feruza,Aygun Muhittin,CEVATEMRE BUSE,ULUKAYA ENGİN. NEW JOURNAL OF CHEMISTRY,
2017 - The role of cell cycle progression for the apoptosis of cancer cells induced by palladium(II)-saccharinate complexes of terpyridine
Kaçar Ömer,CEVATEMRE BUSE,hatipoğlu ibrahim,arda nazlı,ULUKAYA ENGİN,yılmaz veysel turan,açılan ceyda. BIOORGANIC MEDICINAL CHEMISTRY,
2017 - A trans platinum II complex induces apoptosis in cancer stem cells of breast cancer
AZTOPAL NAZLIHAN,KARAKAS DIDEM,CEVATEMRE BUSE,ARI FERDA,ICSEL CEYDA,Daidone MG,ULUKAYA ENGİN. BIOORGANIC MEDICINAL CHEMISTRY,
2017 - Enhanced cytotoxic activity of doxorubicin through the inhibition of autophagy in triple negative breast cancer cell line
AYDINLIK SEYMA,ERKISA MERVE,CEVATEMRE BUSE,SARIMAHMUT MEHMET,DERE EGEMEN,ARI FERDA,ULUKAYA ENGİN. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS,
2017 - Synthesis biological characterization and evaluation of molecular mechanisms of novel copper complexes as anticancer agents
ACILAN CEYDA,CEVATEMRE BUSE,ADIGUZEL ZELAL,KARAKAS DIDEM,ULUKAYA ENGİN,Ribeiro Nadia,Correia Isabel,Pessoa Joao Costa. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS,
2017 - A palladium(II)-saccharinate complex of terpyridine exerts higher anticancer potency and less toxicity than cisplatin in a mouse allograft model
Yüksel Çetin,Adıgüzel Z,Polat HU,Akkoç T,Taş A,CEVATEMRE BUSE,Çelik G,Çarıkçı B,YILMAZ VEYSEL TURAN,ULUKAYA ENGİN,Açılan Ceyda. ANTI-CANCER DRUGS,
2017 - Total Phenolic Content, Antioxidant and Cyto-/Genotoxic Activities of Pelargonium quercetorum Agnew in Human Breast Cancer Cells
ARI FERDA,ÇELİKLER KASIMOĞULLARI SERAP,KARAKAŞ DİDEM,CEVATEMRE BUSE,FIRAT MEHMET,ULUKAYA ENGİN. Journal of Clinical and Experimental Investigations, 8(1), 22-30.
2017 - Folic acid-conjugated cationic Ag2S quantum dots for optical imaging and selective doxorubicin delivery to HeLa cells.
Duman Fatma Demir,Erkisa Merve,Khodadust Rouhullah,ARI FERDA,ULUKAYA ENGİN,Acar Havva Yagci. Nanomedicine, 12(19), 2319-2333.
2017 - Synthesis, structures, DNA/protein binding, molecular docking, anticancer activity and ROS generation of Ni(II ), Cu(II) and Zn(II) 5,5-diethylbarbiturate complexes with bis(2-pyridylmethyl)amine and terpyridine
YILMAZ VEYSEL TURAN,İÇSEL CEYDA,SUYUNOVA FERUZA,AYGÜN MUHİTTİN,CEVATEMRE BUSE,ULUKAYA ENGİN. New Journal of Chemistry, 41(16), 8092-8106.
2017 - Total Phenolic Content, Antioxidant and Cyto-/Genotoxic Activities of Pelargonium quercetorum Agnew in Human Breast Cancer Cells.
ARI FERDA,ÇELİKLER KASIMOĞULLARI SERAP,Karakaş Didem,CEVATEMRE BUSE,FIRAT MEHMET,ULUKAYA ENGİN. Journal of Clinical and Experimental Investigations, 8(1), 22-30.
2017 - Novel 1-(7-ethoxy-1-benzofuran-2-yl) substituted chalcone derivatives: Synthesis, characterization and anticancer activity
COŞKUN DEMET,ERKISA MERVE,ULUKAYA ENGİN,COŞKUN MEHMET FATİH,ARI FERDA. European Journal of Medicinal Chemistry, 136(), 212-222.
2017 - Anti-angiogenic effect of a Palladium(II)-Saccharinate Complex of Terpyridine in vitro and in vivo
ARMUTAK ELİF İLKAY,GÜREL GÜREVİN EBRU,KIYAN HÜLYA TUBA,AYDINLIK ŞEYMA,YILMAZ VEYSEL TURAN,KONTANTİNOS DİMAS,ULUKAYA ENGİN. MICROVASCULAR RESEARCH,
2017 - The MTT viability assay yields strikingly false-positive viabilities although the cells are killed by some plant extracts
KARAKAŞ DİDEM,ARI FERDA,ULUKAYA ENGİN. TURKISH JOURNAL OF BIOLOGY, 41(), 919-925.
2017 - Enhanced cytotoxic activity of doxorubicin through the inhibition of autophagy in triple negative breast cancer cell line
Aydınlık Şeyma,Erkisa Merve,CEVATEMRE BUSE,SARIMAHMUT MEHMET,DERE EGEMEN,ARI FERDA,ULUKAYA ENGİN. Biochimica et Biophysica Acta (BBA) - General Subjects, 1861(2), 49-57.
2017 - Anti angiogenic effect of a Palladium II Saccharinate Complex of Terpyridine in vitro and in vivo
ARMUTAK ELİF İLKAY,GÜREL GÜREVİN EBRU,KIYAN HÜLYA TUBA,AYDINLIK ŞEYMA,YILMAZ VEYSEL TURAN,DIMAS KONSTANTINOS,ULUKAYA ENGİN. Microvascular Research, 109(), 26-33.
2017 - Computer-aided prediction and cytotoxicity evaluation of dithiocarbamates of 9,10-anthracenedione as new anticancer agents
STASEVYCH MARYNA V,ZVARYCH VİKTOR I,LUNİN VOLODYMYR V,DENİZ NAHİDE GÜLŞAH,GÖKMEN ZELİHA,AKGÜN OĞUZHAN,ULUKAYA ENGİN,POROIKOV VLADIMIR V,GLORIOZOVA TATYANA A,VOLODYMYR P NOVIKOV. SAR AND QSAR IN ENVIRONMENTAL RESEARCH, 28(5), 355-366.
2017 - Computer-aided prediction and cytotoxicity evaluation of dithiocarbamates of 9,10-anthracenedione as new anticancer agents
Stasevych Maryna,Viktor Zvarych,Volodymyr Lunin,DENİZ NAHİDE GÜLŞAH,GÖKMEN ZELİHA,Akgun Oguzhan,ULUKAYA ENGİN,Poroikov Vladimir,Gloriozova Tatyana,Novikov Volodymyr. SAR AND QSAR IN ENVIRONMENTAL RESEARCH, 28(5), 355-366.
2017 - Computer-aided prediction and cytotoxicity evaluation of dithiocarbamates of 9,10-anthracenedione as new anticancer agents
Stasevych Maryna,Zvarych Viktor,Lunin Volodymyr,DENİZ NAHİDE GÜLŞAH,Gokmen Zeliha,Akgun Oğuzhan,ULUKAYA ENGİN,Poroikov Vladimir,Gloriozova Tatyana,Novikov Volodymyr. SAR and QSAR in Environmental Research, 28(5), 355-366.
2017 - Combination of esomeprazole with chemotherapeutics results in more pronounced cytotoxic effect via apoptosis on A549 nonsmall-cell lung cancer cell line.
YILMAZTEPE ORAL ARZU,ORAL HALUK BARBAROS,SARIMAHMUT MEHMET,CEVATEMRE BUSE,Ozkaya Güven,Korkmaz Şeniz,ULUKAYA ENGİN. Turkish Journal of Biochemistry-Turk Biyokimya Dergisi, 41(), 231-241.
2017 - Cytotoxic and apoptotic effects of the combination of palladium (II) 5,5-diethylbarbiturate complex with bis(2-pyridylmethyl)amine and curcumin on non small lung cancer cell lines
Tunc Duygu,DERE EGEMEN,Karakas Didem,CEVATEMRE BUSE,YILMAZ VEYSEL TURAN,ULUKAYA ENGİN. Bioorganic & Medicinal Chemistry, 25(5), 1717-1723.
2017 - The role of cell cycle progression for the apoptosis of cancer cells induced by palladium(II)-saccharinate complexes of terpyridine
Kacar Omer,CEVATEMRE BUSE,Hatipoglu Ibrahim,Arda Nazli,ULUKAYA ENGİN,YILMAZ VEYSEL TURAN,Acilan Ceyda. Bioorganic & Medicinal Chemistry, 25(6), 1770-1777.
2016 - Validation data supporting the characterization of novel copper complexes as anticancer agents
Acılan Ceyda,CEVATEMRE BUSE,Adıguzel Zelal,Karakas Didem,ULUKAYA ENGİN,Riberio Nadia,Correia Isabel,Pessoa Joao Costa. Data in Brief, 9(), 1160-1174.
2016 - Cytotoxic Effect of Conyza canadensis (L.) Cronquist on Human Lung Cancer Cell Lines
AYAZ FATMA,SARIMAHMUT MEHMET,KÜÇÜKBOYACI NURGÜN,ULUKAYA ENGİN. Turkish Journal of Pharmaceutical Sciences, 13(), 342-346.
2016 - Apoptosis-inducing Effect of a Palladium(II) Complex-[PdCl(terpy)](sac).2H2O] on Ehrlich Ascites Carcinoma (EAC) in Mice.
Ikitimur-Armutak EIif İlkay,ULUKAYA ENGİN,Gurel-Gurevin Ebru,Yaylim Ilhan,Isbilen-Basok Banu,Sennazli Gulbin,Yuzbasioglu-Ozturk Gulay,Sonmez Kıvılcım,Celik Faruk,Kucukhuseyin Ozlem,Korkmaz Gurbet,YILMAZ VEYSEL TURAN,Zeybek Sakir Umit. In vivo (Athens, Greece), 30(4), 457-64.
2016 - The plant-derived triterpenoid tingenin B is a potent anticancer agent due to its cytotoxic activity on cancer stem cells of breast cancer in vitro
CEVATEMRE BUSE,Botta Bruno,Mori Mattia,Berardozzi Simone,Ingallina Cinzia,ULUKAYA ENGİN. Chemico-Biological Interactions, 260(), 248-255.
2016 - Olive leaf extract containing oleuropein modulates the cytotoxic effect of epirubicin on breast cancer cells depending on the cell line
Korkmaz Seniz,SARIMAHMUT MEHMET,Ozel Mustafa Zafer,ULUKAYA ENGİN. Turkish Journal of Biochemistry-Turk Biyokimya Dergisi, 41(6), 385-392.
2016 - Ni/Cu/Zn 5,5-diethylbarbiturate complexes with 1,10-phenanthroline and 2,2′-dipyridylamine: synthesis, structures, DNA/BSA binding, nuclease activity, molecular docking, cellular uptake, cytotoxicity and the mode of cell death
YILMAZ VEYSEL TURAN,Icsel Ceyda,Suyunova Feruza,Aygun Muhittin,Aztopal Nazlihan,ULUKAYA ENGİN. Dalton Trans., 45(25), 10466-10479.
2016 - Pelargonium quercetorum Agnew induces apoptosis without PARP or cytokeratin 18 cleavage in non-small cell lung cancer cell lines.
Aztopal Nazlihan,CEVATEMRE BUSE,SARIMAHMUT MEHMET,ARI FERDA,DERE EGEMEN,Ozel Mustafa Zafer,Firat Mehmet,ULUKAYA ENGİN. Oncology letters, 12(2), 1429-1437.
2016 - Antigrowth and Apoptosis Inducing Effects of Hypericum Olympicum L. and Hypericum Adenotrichum Spach. on Lung Cancer Cells In Vitro: Involvement of DNA Damage
Aztopal Nazlihan,Erkısa Merve,ÇELİKLER KASIMOĞULLARI SERAP,ULUKAYA ENGİN,ARI FERDA. JOURNAL OF FOOD BIOCHEMISTRY, 40(4), 559-566.
2016 - Evaluation of genotoxic and apoptotic potential of Hypericum adenotrichum Spach. in vitro
SARIMAHMUT MEHMET,Balikci Necmiye,ÇELİKLER KASIMOĞULLARI SERAP,ARI FERDA,ULUKAYA ENGİN,Güleryuz Gürcan,Ozel Mustafa Zafer. Regulatory Toxicology and Pharmacology, 74(), 137-146.
2016 - The levels of caspase cleaved cytokeratin 18 are elevated in serum from patients with lung cancer and helpful to predict the survival
ULUKAYA ENGİN,yilmaztepe arzu,akgoz semra,linder stig,karadag mehmet. Lung Cancer., 56(3), 399-404.
2016 - The involvement of IL 10 IL 6 IFN gamma TNF alpha and TGF beta gene polymorphisms among Turkish lung cancer patients
colakogullari mukaddes,ULUKAYA ENGİN,YILMAZTEPE ORAL ARZU,aymak figen,basturk bilkay,ursavas ahmet,ORAL HALUK BARBAROS. Cell Biochem Funct, 26(3), 283-290.
2016 - The MTT assay yields a relatively lower result of growth inhibition than the ATP assay depending on the chemotherapeutic drugs tested
ULUKAYA ENGİN,ozdikicioglu ferda,oral yilmaztepe arzu,demirci meral. Toxicol In Vitro, 22(1), 232-239.
2015 - Salivary Gland Tumors
Dimas Konstantinos,ULUKAYA ENGİN,Sakellaridis Nikos. Reference Module in Biomedical Sciences,
2015 - Cancer of the Eye (Intraocular Cancer)
Dimas Konstantinos,ULUKAYA ENGİN,Sakellaridis Nikos. Reference Module in Biomedical Sciences,
2015 - Design, Synthesis, Biological Evaluation, and Antioxidant and Cytotoxic Activity of Heteroatom-Substituted 1,4-Naphtho- and Benzoquinones
DENİZ NAHİDE GÜLŞAH,Ibis Cemil,Gokmen Zeliha,Stasevych Maryna,Novikov Volodymyr,Komarovska-Porokhnyavets Olena,Ozyurek Mustafa,Guclu Kubilay,Karakas Didem,ULUKAYA ENGİN. Chemical and Pharmaceutical Bulletin, 63(12), 1029-1039.
2015 - Cationic Pd(II)/Pt(II) 5,5-diethylbarbiturate complexes with bis(2-pyridylmethyl)amine and terpyridine: Synthesis, structures,DNA/BSA interactions, intracellular distribution, cytotoxic activity and induction of apoptosis
Icsel Ceyda,YILMAZ VEYSEL TURAN,Kaya Yunus,Durmus Selvi,SARIMAHMUT MEHMET,BÜYÜKGÜNGÖR ORHAN,ULUKAYA ENGİN. Journal of Inorganic Biochemistry, 152(), 38-52.
2015 - Anti growth effect of a novel trans dichloridobis 2 2 hydroxyethyl pyridine platinum II complex via induction of apoptosis on breast cancer cell lines
YILMAZTEPE ORAL ARZU,CEVATEMRE BUSE,SARIMAHMUT MEHMET,Icsel Ceyda,YILMAZ VEYSEL TURAN,ULUKAYA ENGİN. Bioorganic & Medicinal Chemistry, 23(15), 4303-4310.
2015 - Addition of niclosamide to palladium II saccharinate complex of terpyridine results in enhanced cytotoxic activity inducing apoptosis on cancer stem cells of breast cancer
Didem Karakas,CEVATEMRE BUSE,Aztopal Nazlıhan,ARI FERDA,YILMAZ VEYSEL TURAN,ULUKAYA ENGİN. Bioorganic & Medicinal Chemistry, 23(17), 5580-5586.
2015 - In vitro antibacterial activity of sponge-associated fungi against bacterial aquaculture pathogens.
ALTUNOK MUHAMMET,Ozkaya Ferhat Can,ENGİN SEMİH,TANRIKUL TEVFİK TANSEL,Aydınlık Şeyma,ULUKAYA ENGİN. Fresenius Environmental Bulletin, 24(6A), 2158-2166.
2015 - The M30 assay does not detect apoptosis in epithelial derived cancer cells expressing low levels of cytokeratin 18
CEVATEMRE BUSE,ULUKAYA ENGİN,SARIMAHMUT MEHMET,Yilmaztepe Oral Arzu,Frame Fiona M. Tumor Biology, 36(9), 6857-6865.
2015 - IL-6 originated from breast cancer tissue-derived mesenchymal stromal cells may contribute to carcinogenesis
Sağlam Özlem,Ünal Zehra Seda,Subaşı Cansu,ULUKAYA ENGİN,KARAÖZ ERDAL. Tumor Biology, 36(7), 5667-5677.
2015 - Cytotoxic activity of novel palladium-based compounds on leukemia cell lines
Antunovic Maja,Kriznik Bojana,ULUKAYA ENGİN,YILMAZ VEYSEL TURAN,Mihalic Katarina C,Madunic Josip,Marijanovic Inga. Anti-Cancer Drugs, 26(2), 180-186.
2015 - Anticancer effect of a novel palladium-saccharinate complex of terpyridine by inducing apoptosis on Ehrlich ascites carcinoma (EAC) in Balb-C mice.
Ikitimur-Armutak EIif İlkay,Sonmez Kıvılcım,Akgun-Dar Kadriye,Sennazli Gulbin,Kapucu Aysegul,Yigit Funda,YILMAZ VEYSEL TURAN,ULUKAYA ENGİN. Anticancer research, 35(3), 1491-7.
2015 - A proteomic analysis of p53-independent induction of apoptosis by bortezomib in 4T1 breast cancer cell line
YERLİKAYA AZMİ,OKUR EMRAH,BAYKAL AHMET TARIK,Acılan Ceyda,BOYACI İHSAN,ULUKAYA ENGİN. Journal of Proteomics, 113(), 315-325.
2015 - Promising anticancer activity of a lichen Parmelia sulcata Taylor against breast cancer cell lines and genotoxic effect on human lymphocytes
Ferda Ari,ULUKAYA ENGİN,ORAN SEYHAN,ÇELİKLER KASIMOĞULLARI SERAP,ÖZTÜRK ŞULE,Mustafa Zafer Ozel. Cytotechnology, 67(3), 531-543.
2014 - Data for a proteomic analysis of p53-independent induction of apoptosis by bortezomib in 4T1 breast cancer cell line
YERLİKAYA AZMİ,OKUR EMRAH,BAYKAL AHMET TARIK,Acılan Ceyda,BOYACI İHSAN,ULUKAYA ENGİN. Data in Brief, 1(), 56-59.
2014 - Effects of Off-Pump Versus On-Pump Coronary Artery Bypass Grafting: Apoptosis, Inflammation, and Oxidative Stress
Bicer Murat,Senturk Tunay,Yanar Murat,Tutuncu Ahmet,YILMAZTEPE ORAL ARZU,ULUKAYA ENGİN,SERDAR ZEHRA,Signak Işık Senkaya. The Heart Surgery Forum, 17(5), 271-.
2014 - Cancer stem cells: emerging actors in both basic and clinical cancer research
Karakas Didem,CEVATEMRE BUSE,ULUKAYA ENGİN. Turkish Journal of Biology, 38(6), 829-838.
2014 - Additive enhancement of apoptosis by TRAIL and fenretinide in metastatic breast cancer cells in vitro
ULUKAYA ENGİN,SARIMAHMUT MEHMET,CEVATEMRE BUSE,ARI FERDA,YERLİKAYA AZMİ,Dimas Konstantinos. Biomedicine & Pharmacotherapy, 68(4), 477-482.
2014 - Biochemical and Proteomic Analysis of a Potential Anticancer Agent: Palladium(II) Saccharinate Complex of Terpyridine Acting through Double Strand Break Formation
Adiguzel Zelal,BAYKAL AHMET TARIK,Kacar Omer,YILMAZ VEYSEL TURAN,ULUKAYA ENGİN,Acilan Ceyda. Journal of Proteome Research, 13(11), 5240-5249.
2014 - Evaluation of the molecular mechanisms of a palladium(II) saccharinate complex with terpyridine as an anticancer agent
Kacar Omer,Adiguzel Zelal,YILMAZ VEYSEL TURAN,Cetin Yuksel,CEVATEMRE BUSE,Arda Nazli,BAYKAL AHMET TARIK,ULUKAYA ENGİN,Acilan Ceyda. Anti-Cancer Drugs, 25(1), 17-29.
2014 - Genotoxic, cytotoxic, and apoptotic effects of crude extract of Usnea filipendula Stirt. in vitro
ÇELİKLER KASIMOĞULLARI SERAP,ORAN SEYHAN,ARI FERDA,ULUKAYA ENGİN,Aztopal Nazlihan,SARIMAHMUT MEHMET,ÖZTÜRK ŞULE. Turkish Journal of Biology, 38(6), 940-947.
2014 - Apoptosis-inducing effect of a palladium(II) saccharinate complex of terpyridine on human breast cancer cells in vitro and in vivo
ARI FERDA,CEVATEMRE BUSE,Ikitimur Armutak Elif Ilkay,Aztopal Nazlihan,YILMAZ VEYSEL TURAN,ULUKAYA ENGİN. Bioorganic & Medicinal Chemistry, 22(17), 4948-4954.
2014 - Parmelia sulcata Taylor and Usnea filipendula Stirt induce apoptosis-like cell death and DNA damage in cancer cells
ARI FERDA,Nazlihan Aztopal,ORAN SEYHAN,Bozdemir Sezin,ÇELİKLER KASIMOĞULLARI SERAP,ÖZTÜRK ŞULE,ULUKAYA ENGİN. Cell Proliferation, 47(5), 457-464.
2014 - Genotoxic, cytotoxic, and apoptotic effects of Hypogymnia physodes (L.) Nyl. on breast cancer cells
ARI FERDA,ÇELİKLER KASIMOĞULLARI SERAP,ORAN SEYHAN,Balikci Necmiye,Ozturk Sule,Ozel Mustafa Zafer,Ozyurt Dilek,ULUKAYA ENGİN. Environmental Toxicology, 29(7), 804-813.
2014 - Isolation of Major Phenolic Compounds from the Extracts of Prunella L. Species Grown in Turkey and Their Antioxidant and Cytotoxic Activities
SAHIN SALIHA,ARI FERDA,DEMIR CEVDET,ULUKAYA ENGİN. JOURNAL OF FOOD BIOCHEMISTRY, 38(2), 248-257.
2013 - Can safe and long-term exposure to extremely low frequency (50 Hz) magnetic fields affect apoptosis, reproduction, and oxidative stress?
Akdag Mehmet Zulkuf,Dasdag Suleyman,Uzunlar Ali Kemal,ULUKAYA ENGİN,YILMAZTEPE ORAL ARZU,Çelik Necla,Akşen Feyzan. International Journal of Radiation Biology, 89(12), 1053-1060.
2013 - Promising anti-growth effects of palladium(II) saccharinate complex of terpyridine by inducing apoptosis on transformed fibroblasts in vitro
Coskun Melis Debreli,ARI FERDA,YILMAZTEPE ORAL ARZU,SARIMAHMUT MEHMET,KUTLU HATİCE MEHTAP,YILMAZ VEYSEL TURAN,ULUKAYA ENGİN. Bioorganic & Medicinal Chemistry, 21(15), 4698-4705.
2013 - Differential Cytotoxic Activity of a Novel Palladium-Based Compound on Prostate Cell Lines, Primary Prostate Epithelial Cells and Prostate Stem Cells
ULUKAYA ENGİN,Frame Fiona M,CEVATEMRE BUSE,Pellacani Davide,Walker Hannah,Mann Vincent M,Simms Matthew S,Stower Michael J,YILMAZ VEYSEL TURAN,Maitland Norman J,Afarinkia Kamyar. PLoS ONE, 8(5), 64278-.
2013 - Palladium(II) saccharinate complexes with bis(2-pyridylmethyl)amine induce cell death by apoptosis in human breast cancer cells in vitro
ARI FERDA,ULUKAYA ENGİN,SARIMAHMUT MEHMET,YILMAZ VEYSEL TURAN. Bioorganic & Medicinal Chemistry, 21(11), 3016-3021.
2013 - Synthesis structural characterization and cell death inducing effect of novel palladium II and platinum II saccharinate complexes with 2 hydroxymethyl pyridine and 2 2 hydroxyethyl pyridine on cancer cells in vitro
ARI FERDA,aztopal nazlihan,icsel ceyda,YILMAZ VEYSEL TURAN,guney emel,BÜYÜKGÜNGÖR ORHAN,ULUKAYA ENGİN. Bioorganic & Medicinal Chemistry, 21(21), 6427-6434.
2013 - Combination of fenretinide and indole-3-carbinol results in synergistic cytotoxic activity inducing apoptosis against human breast cancer cells in vitro
CEVATEMRE BUSE,ARI FERDA,SARIMAHMUT MEHMET,YILMAZTEPE ORAL ARZU,DERE EGEMEN,Kacar Omer,Adiguzel Zelal,Acilan Ceyda,ULUKAYA ENGİN. Anti-Cancer Drugs, 24(), 1-.
2013 - Synthesis, crystal structures, DNA binding and cytotoxicity of two novel platinum(II) complexes containing 2-(hydroxymethyl)pyridine and pyridine-2-carboxylate ligands
Icsel Ceyda,YILMAZ VEYSEL TURAN,Golcu Aysegul,ULUKAYA ENGİN,Buyukgungor Orhan. Bioorganic & Medicinal Chemistry Letters, 23(7), 2117-2122.
2013 - Changes in Gene Methylation Following Chemotherapyin Breast Cancer Cell Lines
ARI FERDA,Napieralski Rudolf,ULUKAYA ENGİN. Turkish Journal of Biochemistry-Turk Biyokimya Dergisi, 38(2), 34-42.
2013 - trans Dichloridopalladium II and platinum II complexes with 2 hydroxymethyl pyridine and 2 2 hydroxyethyl pyridine Synthesis structural characterization DNA binding and in vitro cytotoxicity studies
icsel ceyda,YILMAZ VEYSEL TURAN,ARI FERDA,ULUKAYA ENGİN,harrison William T. European Journal of Medicinal Chemistry, 60(), 386-394.
2012 - Peripherally located A431 cells are more sensitive to cell death induced by exogenous oxidative stress.
ARI FERDA,SARIMAHMUT MEHMET,ULUKAYA ENGİN. Current Signal Transduction Therapy, 7(3), 202-208.
2012 - The p53 independent induction of apoptosis in breast cancer cells in response to proteasome inhibitor bortezomib
YERLİKAYA AZMİ,OKUR EMRAH,ULUKAYA ENGİN. Tumor Biology, 33(5), 1385-1392.
2011 - A glance at the methods for detection of apoptosis qualitatively and quantitatively
ULUKAYA ENGİN,ACILAN CEYDA,ARI FERDA,IKITIMUR ELIF,YILMAZ YUSUF. Turkish Journal of Biochemistry,
2011 - Modulation of protein expression levels and DNA methylation status of breast cancer metastasis genes by anthracycline-based chemotherapy and the demethylating agent decitabine
ARI FERDA,NAPIERALSKI RUDOLF,ULUKAYA ENGİN,DERE EGEMEN,COLLING CRISTOPH,HONERT KATJA,ACHIM KRUGER,KIECHLE MARION. Cell Biochemistry and Function, 29(8), 651-659.
2011 - Chemotherapy increases caspase-cleaved cytokeratin 18 in the serum of breast cancer patients
ULUKAYA ENGİN,KARAAGAC ESRA,ARI FERDA,YILMAZTEPE ORAL ARZU,SADUMAN ADIM,TOKULLUGIL ASUMAN,EVRENSEL TURKKAN. Radiology and Oncology, 45(2), 116-22.
2011 - The Expressions of pAkt and PTEN in Lung Cancer Patients 24 Hours After the Cisplatin-Based Chemotherapy: A Prospective Pilot Study
ULUKAYA ENGİN,YAGCI ARTAY,BERRIN ZIK,ALPER SEVIMLI,YILMAZTEPE ORAL ARZU,ARI FERDA,AKGOZ SEMRA,BAYER SIBEL,URSAVAS AHMET. International Journal of Hematology and Oncology,
2011 - Circulating Levels of Vascular Endothelial Growth Factor A and Its Soluble Receptor in Patients with Biopsy-proven Nonalcoholic Fatty Liver Disease
YILMAZ YUSUF,OYA YONAL,KURT RAMAZAN,ALAHDAB YESIM OZEN,OSMAN OZDOGAN,CIGDEM ATAIZI CELIKEL,ULUKAYA ENGİN,NESE IMERYUZ,KALAYCI CEM,AVSAR EROL. Archives of Medical Research, 42(1), 38-43.
2011 - Synthesis, characterization, structures and cytotoxic activity of palladium(II) and platinum(II) complexes containing bis(2-pyridylmethyl)amine and saccharinate
GUNEY EMEL,YILMAZ VEYSEL TURAN,ARI FERDA,ORHAN BUYUKGUNGOR,ULUKAYA ENGİN. Polyhedron,
2011 - Toward a Biochemical Diagnosis of NASH: Insights From Pathophysiology For Distinguishing Simple Steatosis From Steatohepatitis
YILMAZ VEYSEL TURAN,ULUKAYA ENGİN. CURRENT MEDICINAL CHEMISTRY, 18(5), 725-732.
2011 - Anti-cancer activity of a novel palladium(II) complex on human breast cancer cells in vitro and in vivo
ULUKAYA ENGİN,ARI FERDA,DIMAS KONSTANTINOS,IKITIMUR ELIF ILKAY,GUNEY EMEL,YILMAZ VEYSEL TURAN. European Journal of Medicinal Chemistry, 46(10), 4957-4963.
2011 - Cell death-inducing effect of novel palladium(II) and platinum(II) complexes on non-small cell lung cancer cells in vitro
ULUKAYA ENGİN,ARI FERDA,DIMAS KONSTANTINOS,SARIMAHMUT MEHMET,GUNEY EMEL,SAKELLARIDIS NIKOS,YILMAZ VEYSEL TURAN. Journal of Cancer Research and Clinical Oncology, 137(10), 1425-1434.
2011 - Apoptosis: why and how does it occur in biology?
ULUKAYA ENGİN,acilan ceyda,yilmaz yusuf. Cell Biochemistry and Function, 29(6), 468-480.
2010 - Serum levels of osteoprotegerin in the spectrum of nonalcoholic fatty liver disease
YILMAZ YUSUF,YONAL OYA,KURT RAMAZAN,YILMAZTEPE ORAL ARZU,EREN FATIH,OZDOGAN OSMAN,ARI FERDA,CELIKEL CIGDEM A,KORKMAZ SENIZ,ULUKAYA ENGİN,IMERYUZ NESE,KALAYCI CEM,AVSAR EROL. Scandinavian Journal of Clinical and Laboratory Investigation, 70(8), 541-546.
2010 - Molecular signatures of nonalcoholic fatty liver disease: The present and future
YILMAZ YUSUF,ULUKAYA ENGİN. Hepatology, 51(5), 1866-1866.
2010 - Serum fetuin A/ 2HS-glycoprotein levels in patients with non-alcoholic fatty liver disease: relation with liver fibrosis
YILMAZ YUSUF,YONAL OYA,KURT RAMAZAN,ARI FERDA,YILMAZTEPE ORAL ARZU,CELIKEL A CIGDEM,KORKMAZ SENIZ,ULUKAYA ENGİN,OZDOGAN OSMAN,IMERYUZ NESE,AVSAR EROL,KALAYCI CEM. Annals of Clinical Biochemistry, 47(6), 549-553.
2010 - The ATP assay, but not the MTT assay, detects further cytotoxicity of the combination of anthracyline-based therapy with histone deacetylase inhibitor (Valproic acid) in breast cancer cells
ARI FERDA,IKITIMUR ELIF,ULUKAYA ENGİN. turkish journal of biochemistry,
2010 - Effects of Extremely Low-Frequency Magnetic Field on Caspase Activities and Oxidative Stress Values in Rat Brain
AKDAG MEHMET ZULKUF,DASDAG SULEYMAN,ULUKAYA ENGİN,UZUNLAR ALI KEMAL,KURT MUSTAFA AYBERK,ABDULLAH TASKIN. Biological Trace Element Research, 138(1-3), 238-249.
2010 - Soluble cytokeratin 18 biomarkers may provide information on the type of cell death during early ischemia and reperfusion periods of liver transplantation
ULUKAYA SEZGIN,ULUKAYA ENGİN,ISIK ALPER,YILMAZTEPE ORAL ARZU,KILIC MURAT. Clinical Transplantation, 24(6), 848-854.
2010 - sFas levels increase in response to cisplatin-based chemotherapy in lung cancer patients
ULUKAYA ENGİN,ACILAN CEYDA,Meryem Yilmaz,YILMAZTEPE ORAL ARZU,ARI FERDA,ZIK BERRIN,URSAVAS AHMET,TOKULLUGIL H ASUMAN. Cell Biochemistry and Function, 28(7), 565-570.
2010 - Utilization of cytokeratin-based biomarkers for pharmacodynamic studies
LINDER STIG,OLOFSSON MARIA HAGG,HERMANN RICHARD,ULUKAYA ENGİN. Expert Review of Molecular Diagnostics, 10(3), 353-359.
2010 - Comparative effects of pioglitazone and rosiglitazone on plasma levels of soluble receptor for advanced glycation end products in type 2 diabetic patients.
OZEN OZ GUL,TUNCEL ERCAN,YILMAZ YUSUF,ULUKAYA ENGİN,GUL CUMA BULENT,KIYICI SINEM,YILMAZTEPE ORAL ARZU,GUCLU METIN,ERSOY CANAN,SAZI IMAMOGLU. Metabolism,
2009 - . Proteomic analysis of serum in patients with nonalcoholic steatohepatitis using MALDI-TOF/MS.
ULUKAYA ENGİN,YILMAZ YUSUF,Moshkovskii Sergei,MARIA KARPOVA,PYATNITSKIY MIKHAIL,ATUG OZLEN,DOLAR MAHMUT ENVER. Scandinavian Journal of Gastroenterology,
2009 - Apoptosis-Inducing Effects of Morinda citrifolia L. (Noni) and Doxorubicin on the Ehrlich Ascites (EAC) Tumor in Balb-c Mice
IKITIMUR ELIF,DAR AKGUN KADRIYE,AYSEGUL KAPUCU,ESMA OSANC,HUSNIYE DOGRUMAN,HAKAN ERALTAN,ULUKAYA ENGİN. Cell Biochemistry and Function,
2009 - Effect of Mobile Phone Exposure on Apoptotic Glial Cells and Status of Oxidative Stress in Rat Brain
DASDAG SULEYMAN,AKDAG M ZULKUF,ULUKAYA ENGİN,UZUNLAR ALI KEMAL,OCAK ALI RIZA. Electromagnetic Biology and Medicine, 28(4), 342-354.
2009 - Serial changes in circulating M30 antigen, a biomarker of apoptosis, in patients with acute coronary syndromes: relationship with the severity of coronary artery disease
SENTURK TUNAY,AYDINLAR ALI,YILMAZ YUSUF,YILMAZTEPE ORAL ARZU,OZDABAKOGLU OSMAN,ULUKAYA ENGİN. Coronary Artery Disease, 20(8), 494-498.
2009 - Serum concentrations of human angiopoietin-like protein 3 in patients with nonalcoholic fatty liver disease: association with insulin resistance
YILMAZ YUSUF,ULUKAYA ENGİN,ATUG OZLEN,DOLAR MAHMUT ENVER. European Journal of Gastroenterology & Hepatology, 21(11), 1247-1251.
2009 - Elevated serum levels of caspase-cleaved cytokeratin 18 (CK18-Asp396) in patients with nonalcoholic steatohepatitis and chronic hepatitis C.
YILMAZ YUSUF,DOLAR MAHMUT ENVER,ULUKAYA ENGİN,AKGOZ SEMRA,KESKIN MURAT,KIYICI MURAT,YERCI OMER,YILMAZTEPE ORAL ARZU,CUMA BULENT GUL,GUREL SELIM,NAK SELİM GİRAY,MACIT GULTEN. Medical science monitor : international medical journal of experimental and clinical research, 15(4), 189-93.
2009 - Decreased plasma levels of soluble receptor for advanced glycation endproducts (sRAGE) in patients with nonalcoholic fatty liver disease
YILMAZ YUSUF,ULUKAYA ENGİN,GUL OZ OZEN,MAHMUT ARABUL,GUL BULENT CUMA,OZLEN ATUG,YILMAZTEPE ORAL ARZU,AKER SIBEL,DOLAR MAHMUT ENVER. Clinical Biochemistry, 42(9), 802-807.
2009 - The quest for liver fibrosis biomarkers: Promises from the enhanced liver fibrosis panel and beyond
YILMAZ YUSUF,ULUKAYA ENGİN,DOLAR MAHMUT ENVER. Hepatology, 49(3), 1056-1057.
2009 - Commentary on the study of Vos et al. "Cytokeratin 18, a marker of cell death, is increased in children with suspected nonalcoholic fatty liver disease
YILMAZ YUSUF,DOLAR MAHMUT ENVER,ULUKAYA ENGİN. Journal of Pediatric Gastroenterology and Nutrition,
2009 - Serum M30 levels: A potential biomarker of severe liver disease in nonalcoholic fatty liver disease and normal aminotransferase levels
YILMAZ YUSUF,ULUKAYA ENGİN,DOLAR MAHMUT ENVER. Hepatology, 49(2), 697-697.
2008 - "A biomarker biopsy” for the diagnosis of NASH: promises from CK-18 fragments
YILMAZ YUSUF,ULUKAYA ENGİN,DOLAR MAHMUT ENVER. Obesity surgery,
2008 - Cytokine Gene Polymorphism and Postreperfusion Syndrome During Orthotopic Liver Transplantation
ULUKAYA SEZGIN,BASTURK BILKAY,Kılıç MU,ULUKAYA ENGİN. Transplantation Proceedings, 40(5), 1290-1293.
2008 - The Differential Anticancer Effects of Green Tea in Estrogen Receptor-Positive and Estrogen Receptor-Negative Human Breast Cancer Cell Lines.
OZDIKICIOGLU FERDA,ULUKAYA ENGİN,YILMAZTEPE ORAL ARZU,OZEL MUSTAFA,OZKAN KUTLULAR. advances in molecular medicine,
2008 - The MTT assay yields a relatively lower result of growth inhibition than the ATP assay depending on the chemotherapeutic drugs tested.
ULUKAYA ENGİN,OZDIKICIOGLU FERDA,YILMAZTEPE ORAL ARZU,MERAL DEMIRCI. Toxicology in vitro, 22(1), 232-239.
2008 - Mobile phone exposure does not induce apoptosis on spermatogenesis in rats
DASDAG SULEYMAN,AKDAG MEHMET ZULKUF,ULUKAYA ENGİN,UZUNLAR AHMET KEMAL,YEGIN DILEK. Archives of Medical Research, 39(1), 40-44.
2008 - Does sphingosine-1-phosphate have a protective effect on cyclophosphamide- and irradiation-induced ovarian damage in the rat model?
KAYA HAKAN,DESDICIOGLU RAZIYE,SEZIK MEKIN,ULUKAYA ENGİN,OZKAYA OKAN,YILMAZTEPE ORAL ARZU,DEMIRCI MERAL. Fertility and sterility, 89(3), 732-735.
2008 - The involvement of IL-10, IL-6, IFN-gamma, TNF-alpha and TGF-beta gene polymorphisms among Turkish lung cancer patients.
COLAKOGULLARI MUKADDES,ULUKAYA ENGİN,YILMAZTEPE ORAL ARZU,AYMAK FIGEN,BASTURK BILKAY,URSAVAS AHMET,ORAL HALUK BARBAROS. Cell biochemistry and function, 26(3), 283-290.
2007 - VEGF, VEGF-receptors and lung cancer
YILMAZTEPE ORAL ARZU,ULUKAYA ENGİN,YILMAZ YUSUF. Advances in molecular medicine,
2007 - Clinical significance of activity of ALT enzyme in patients with hepatitis C virus.
AKKAYA ONDER,KIYICI MURAT,YILMAZ YUSUF,ULUKAYA ENGİN,YERCI OMER. World journal of gastroenterology, 13(41), 5481-5485.
2007 - Soluble vascular endothelial growth factor receptor-1 (sVEGFR-1) is decreased in lung cancer patients showing progression: a pilot study.
YILMAZTEPE ORAL ARZU,ULUKAYA ENGİN,BERRİN ZİK,YAGCI ARTAY,SEVIMLI ALPER,YILMAZ MERYEM,ERDOGAN BAHADIR,KOC MEHMET,AKGOZ SEMRA,MEHMET KARADAG,TOKULLUGIL ASUMAN. Cancer investigation, 25(5), 322-327.
2007 - Soluble forms of extracellular cytokeratin 18 may differentiate simple steatosis from nonalcoholic steatohepatitis.
YILMAZ YUSUF,DOLAR MAHMUT ENVER,ULUKAYA ENGİN,AKGOZ SEMRA,KESKIN MURAT,KIYICI MURAT,AKER SIBEL,YILMAZTEPE ORAL ARZU,GUREL SELIM,MACIT GULTEN,NAK SELİM GİRAY. World journal of gastroenterology, 13(6), 837-844.
2007 - The levels of caspase-cleaved cytokeratin 18 are elevated in serum from patients with lung cancer and helpful to predict the survival.
ULUKAYA ENGİN,YILMAZTEPE ORAL ARZU,AKGOZ SEMRA,LINDER STIG,MEHMET KARADAG. Lung cancer (Amsterdam, Netherlands), 56(3), 399-404.
2007 - Soluble forms of extracellular cytokeratin 18 may differentiate simple steatosis from nonalcoholic steatohepatitis
YILMAZ YUSUF,DOLAR MAHMUT ENVER,ULUKAYA ENGİN,AKGÖZ SEMRA,keskin murat,KIYICI MURAT,aker sibel,yilmaztepe arzu,GÜREL SELİM,GÜLTEN MACİT,NAK SELİM GİRAY. World J Gastroenterol., 13(6), 837-844.
2006 - Higher serum nitrate levels are associated with poor survival in lung cancer patients.
MUKADDES COLAKOGULLARI,ULUKAYA ENGİN,YILMAZTEPE ORAL ARZU,GOKHAN OCAKOGLU,YILMAZ MERYEM,KARADAG MEHMET,TOKULLUGIL ASUMAN. Clinical biochemistry, 39(9), 898-903.
2006 - Response to neoadjuvant chemotherapy in breast cancer could be predictable by measuring a novel serum apoptosis product, caspase-cleaved cytokeratin 18: a prospective pilot study.
DEMIRAY MUTLU,ULUKAYA ENGİN,ARSLAN MURAT,GOKGOZ SEHSUVAR,OZLEM SARAYDAROGLU,ERCAN ILKER,EVRENSEL TURKKAN,OSMAN MANAVOGLU. Cancer investigation, 24(7), 669-76.
2005 - Investigation of fecal pancreatic elastase-1 levels in type 2 diabetic patients.
YILMAZTEPE ORAL ARZU,ULUKAYA ENGİN,ERSOY CANAN,YILMAZ MERYEM,TOKULLUGIL ASUMAN. The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 16(2), 75-80.
2005 - Effects of raloxifene on serum malondialdehyde, erythrocyte superoxide dismutase, and erythrocyte glutathione peroxidase levels in healthy postmenopausal women.
KAYA HAKAN,OZKAYA OKAN,SEZIK MEKIN,ARSLANOGLU EVRIM,YILMAZTEPE ORAL ARZU,ULUKAYA ENGİN. Maturitas, 50(3), 182-188.
2004 - Cytokine gene polymorphism and early graft rejection in liver transplant recipients.
KARASU ZEKI,ULUKAYA SEZGIN,AYANOGLU OMER,BASTURK BİLKAY,ULUKAYA ENGİN,AKYILDIZ MURAT,TOKAT YAMAN. Transplantation proceedings, 36(9), 2791-2795.
2004 - Evaluation of the effects of helicobacter pylori eradication therapy on gastric antral epithelial hyperproliferation: a prospective, sixth-month follow-up study.
DEMIRAY MUTLU,GULTEN MACIT,MANAVOGLU OSMAN,EVRENSEL TURKKAN,ULUKAYA ENGİN,YERCI OMER,KANAT OZKAN,KURT ENDER,ARSLAN MURAT,GONULLU GUZIN,DEMIRAY HULYA,GULTEN TUNA,MEMIK FARUK. Hepatogastroenterology, 51(59), 1531-1535.
2004 - Interference by anti-cancer chemotherapeutic agents in the MTT-tumor chemosensitivity assay
ULUKAYA ENGİN,COLAKOGULLARI MUKADDES,WOOD EDWARD. Chemotherapy, 50(1), 43-50.
2004 - Interference by Anti Cancer Chemotherapeutic Agents in the MTT Tumor Chemosensitivity Assay
ULUKAYA ENGİN,colakogullari mukaddes,wood ej. Chemotherapy, 50(1), 43-50.
2003 - Fenretinide induces cytochrome c release, caspase 9 activation and apoptosis in the absence of mitochondrial membrane depolarisation
ULUKAYA ENGİN,PIRIANOV GRISHA,KURT MUSTAFA AYBERK,WOOD EDWARD,MEHMET HUSEYIN. Cell death and differentiation, 10(7), 856-859.
2001 - 4-(N-Hydroxyphenyl)retinamide can Selectively Induces Apoptosis in Human Epidermoid Carcinoma Cells but not in Normal Dermal Fibroblasts.
ULUKAYA ENGİN,KURT MUSTAFA AYBERK,WOOD EDWARD. CANCER INVESTIGATION, 19(2), 145-154.
1999 - Fenretinide and Its Relation to Cancer
ULUKAYA ENGİN,WOOD EDWARD. CANCER TREATMENT REVIEWS, 25(4), 229-235.
1999 - The effect of melatonin on lipid peroxidation during radiotherapy in female rats
KAYA HAKAN,DELİBAŞ NAMIK,SERTESER MUSTAFA,ULUKAYA ENGİN,OZKAYA OKAN. STRAHLENTHERAPIE UND ONKOLOGIE, 175(6), 285-288.
1995 - General Practitioners' Opinions about the Basic Sciences in Relation to Medicine
ULUKAYA ENGİN,GULER ASUMAN. biochemical education, 23(3), 143-143.
- Total Phenolic Content, Antioxidant and Cyto-/Genotoxic Activities of Pelargonium quercetorum Agnew in Human Breast Cancer Cells
ARI FERDA,ÇELİKLER KASIMOĞULLARI SERAP,Didem Karakas,CEVATEMRE BUSE,FIRAT MEHMET,ULUKAYA ENGİN. Journal of Clinical and Experimental Investigations,
Moleküler Kanser Biyolojisi
2018 - Türkçe, Bilimsel Kitap ISBN: 9786052329306
Cevatemre Buse,AZTOPAL NAZLIHAN,ULUKAYA ENGİN
(2018), "Combination Therapy with Valproic Acid and Cu (II)- Barbiturate Complex InducesROS-Mediated Apoptosis in Breast Cancer Stem Cell", "Uluslararası", "Sağlık Bilimleri Temel Alanı->Tıbbi Biyoloji",
(2017), "Palladıum Incorporated Mıcelle: A Promısıng Materıal For Future Non-Small Cell Lung Cancer", "Uluslararası", "Sağlık Bilimleri Temel Alanı->Farmasotik Teknoloji",
(2017), "Chloroquine improves the anticancer effectsof doxorubicin in vitro and in vivo models on Mouse Mammary Tumor Ehrlich ascites carcinoma (EAC)", "Uluslararası", "Sağlık Bilimleri Temel Alanı->Veterinerlik Histoloji ve Embriyolojisi",
(2019), "Effects of novel targeted anticancer drugs on cytotoxicity, apoptosis, angiogenesis, EMT, drug resistance and autophagic mechanism", "Uluslararası", "Fen Bilimleri ve Matematik Temel Alanı->Biyoloji", "10.1093/annonc/mdz238.030",
(2018), "Paklitaksel tedavisinin meme kanseri kanser kök hücrelerinde miRNA ekspresyon profiline etkisi", "Uluslararası", "Sağlık Bilimleri Temel Alanı->SAĞLIKLA İLGİLİ ÇOK DİSİPLİNLİ BİLİMLER",
(2017), "Cytotoxic Activites of 3-bromo-5-chloro-2-hydroxyacetophenone-N-phenyl-thiosemicarbazone and 3-bromo-5-chloro-2-hydroxy-acetophenone-N-phenylthiosemicarbazidato triphenylphosphine Nickel(II) Complex Against MCF-7 (Cancer)", "Uluslararası", "Fen Bilimleri ve Matematik Temel Alanı->Kimya",
(2017), "Thiosemicarbazone and Nickel(II) Complex Activites Against DU145 Cells", "Uluslararası", "Fen Bilimleri ve Matematik Temel Alanı->Kimya",
(2017), "The cytotoxic activities of substitue-salicylaldehyde-S-methyl-thiosemicarbazone and it’s complex against MCF-7 cell line", "Uluslararası", "Fen Bilimleri ve Matematik Temel Alanı->Kimya",
(2017), "N-Substituted Thiosemicarbazones - Synthesis,Characterization and Comparison of Cytotoxicities Against MCF 7 Cell", "Uluslararası", "Fen Bilimleri ve Matematik Temel Alanı->Kimya",
(2017), "Özgün bir palladyum-barbitürat bileşiğinin anti-kanser ilaç adayı olarak preklinik analizi", "Ulusal", "Fen Bilimleri ve Matematik Temel Alanı->Biyoloji",
(2018), "TARGETING BREAST CANCER STEM CELLS VIA DUALINHIBITION OF WNT SIGNALING AND HISTONE DEACETYLATION", "Uluslararası", "Fen Bilimleri ve Matematik Temel Alanı->Biyoloji",
(2017), "Benzofuran İçeren Yeni Kalkon Bileşiklerinin Kolon Kanseri Üzerine olan Sitotoksik/Apoptotik Etkilerinin İncelenmesi", "Uluslararası", "Fen Bilimleri ve Matematik Temel Alanı->Moleküler Biyoloji ve Genetik",
"The Other Faces of Death: Cell Type Dependent Apoptotic Effects of Dinuclear Pd (II) Compound", "Uluslararası", "Sağlık Bilimleri Temel Alanı->Tıbbi Onkoloji",
"Dual inhibition of Wnt/beta-catenin signaling and histone deacetylation as a new strategy to eliminate breast cancer stem cells by augmentation of apoptosis", "Uluslararası", "Fen Bilimleri ve Matematik Temel Alanı->Moleküler Biyoloji ve Genetik",
(2018), "Türkiye’de Yetişen Chrysophthalmum Schultz Bıp. Türleri Üzerinde Farmakognozik Araştırmalar", "Ulusal", "Sağlık Bilimleri Temel Alanı->Farmakognozi ve Farmasotik Botanik",
(2018), "The anti-angiogenic effect of the Palladium(ll) Complex-[PdCI(terpy)](sac).2H20] on HUVECs tube formation and in vivo CAM assay", "Uluslararası", "Sağlık Bilimleri Temel Alanı->Tıbbi Biyokimya",
"SYNTHESIS, CHARACTERIZATION AND PHARMACOLOGICAL STUDIES OF SOME NEW MANNICH BASES DERIVED FROM 1,2,4-TRIAZOLES", "Uluslararası", "Sağlık Bilimleri Temel Alanı->Farmasotik Kimya",
(2017), "INVESTIGATION OF ANTI-CANCER ACTIVITY OF ADANSONIADIGITATA (BAOBAB) IN DIFFERENT CANCER CELLS", "Uluslararası", "Fen Bilimleri ve Matematik Temel Alanı->Biyoloji",
(2017), "Cytotoxıc Effect of Dıfferent Extracts of Salvıa Candıdıssıma Vahl. Ssp.candıdıssıma on Lung Cancer Cells.", "Uluslararası", "Fen Bilimleri ve Matematik Temel Alanı->Biyoloji",
(2017), "Palladium Incorporated Micelle: A Promising Material for Future Non-Small Cell Lung Cancer.", "Uluslararası", "Fen Bilimleri ve Matematik Temel Alanı->Biyoloji",
(2017), "Palladium nanoparticles selectively ınduce apoptosis in lung cancer cells through reactive oxygen species.", "Uluslararası", "Fen Bilimleri ve Matematik Temel Alanı->Biyoloji",
(2017), "Cytotoxic/Apoptotic effects of the benzofuran-substituted chalcone derivatives in colon cancer.", "Uluslararası", "Fen Bilimleri ve Matematik Temel Alanı->Biyoloji",
"Pristimerin’in Meme Kanseri Hücreleri Üzerine in vitro ve in vivo Sitotoksik Etkisi", "Ulusal", "Fen Bilimleri ve Matematik Temel Alanı->Biyoloji",
(2017), "N-Substituted Thiosemicarbazones-Synthesis, Characterization and Comparison of Cytotoxicities Against MCF 7 Cell", "Uluslararası", "Fen Bilimleri ve Matematik Temel Alanı->Kimya",
(2017), "CYTOTOXIC EFFECT OF DIFFERENT EXTRACTS OF SALVIACANDIDISSIMA VAHL. SSP. CANDIDISSIMA ON LUNG CANCERCELLS", "Uluslararası", "Fen Bilimleri ve Matematik Temel Alanı->Biyoloji",
(2017), "Chloroquine improves the anticancer effects of doxorubicin in vitro and in vivo models on Mouse Mammary Tumor Ehrlich ascites carcinoma (EAC)", "Uluslararası", "Sağlık Bilimleri Temel Alanı->Histoloji ve Embriyoloji",
(2017), "Investigation of Anti-Cancer Activity of Adansonia digitata (Baobab) In Different Cancer Cells.", "Uluslararası", "Fen Bilimleri ve Matematik Temel Alanı->Biyoloji",
(2017), "Reversal of Unresponsive Lung Cancer Cases Treated on the Basis of an Ex Vivo Tumor Chemosensitivity Assay (Onkogram®).", "Uluslararası", "Fen Bilimleri ve Matematik Temel Alanı->Biyoloji",
(2017), "PALLADIUM INCORPORATED MICELLE: A PROMISING MATERIAL FOR FUTURE NON-SMALL CELL LUNG CANCER", "Uluslararası", "Sağlık Bilimleri Temel Alanı->Farmasotik Biyoteknoloji",
(2017), "Computer-Aided Prediction and Experimental Evaluation of Dithiocarbamates of 9,10-Anthracenedione as New Anticancer Agents", "Uluslararası", "Fen Bilimleri ve Matematik Temel Alanı->Kimya",
(2015), "Mammospheres Cancer Stem Cell Enriched Population in Breast Cancer Show Resistance Against A Palladium II Saccharinate Complex of Terpyridine", "Uluslararası", "Sağlık Bilimleri Temel Alanı->Tıbbi Biyoloji",
(2015), "Palladium II Based Novel Approach to Kill Cancer Stem Cells of Breast Cancer", "Uluslararası", "Sağlık Bilimleri Temel Alanı->Tıbbi Biyoloji",
(2015), "Inhibition of sonic hedgehog pathway in breast cancer stem cells does not provide extra benefit in cytotoxicity resulted from Pd II saccharinate complex of terpyridine", "Uluslararası", "Sağlık Bilimleri Temel Alanı->Tıbbi Biyoloji",
(2015), "Palladium II based anticancer compounds A new hope or an illusion", "Uluslararası", "Sağlık Bilimleri Temel Alanı->Tıbbi Biyoloji",