Faculty of Medicine

Academic Members

Ilknur Dursun

Ilknur Dursun,  Faculty Member, PhD

Faculty Member

Asst. Prof. Dr. İlknur Dursun graduated from Ankara University, Faculty of Science, Department of Biology in 2000. She started working as a research assistant in the Department of Biological Sciences at the Middle East Technical University (METU) Faculty of Arts and Sciences in 2002 and received her MSc degree in January 2005 with her thesis on the subject " Effects Of Prenatal Alcohol Exposure On Activiy, Anxiety And Learning In Young Adult Wistar Rats ". In 2005, she conducted research for 3 months by receiving scholarships from Louisiana State University, Health Sciences Center, Cell Biology and Anatomy Department and METU. Between 2007-2009, she worked at the University of California Davis (UCDavis), Department of Neurobiology, Physiology and Behavior and Neuroscience Center to do her doctoral thesis in collaboration with METU-UCDavis research program,. In February 2011, she completed her doctorate degree on " The Effects Of Early Postnatal Ethanol Intoxication On Retina Ganglion Cell Morphology And The Development Of Retino-Geniculate Projections In Mice”. She worked at different foundation universities between 2012-2020. As of November 2020, as a faculty member at İstinye University, Faculty of Medicine, Department of Physiology, she continues to investigate the effects of toxin exposure (e.g., ethanol) on brain development and behavior on animal models in the perinatal period (prenatal and/or postnatal). She models teratogenic substances in experimental animals with the intubation technique that she successfully applies to newborn mice (0-10 days). Within the scope of preclinical studies, she tests behaviors such as learning and memory, anxiety, locomotor activity, depression by using very broad behavioral tests such as Rotarod/Accelerod, Open Field Test, Forced Swimming Test, Plus Maze, 12-Arm Radial Maze and Morris Water Maze for disorders created in experimental animal models. In addition to behavioral experiments, she performs quantitative neuroanatomical examinations of brain tissue images, which obtained by immunohistochemistry and other staining methods, while using StereoInvestigator and Neurolucida hardware and software (mbfbioscience technology).

Research Areas: Experimental Brain Research, Behavioral Neuroscience, Developmental Neuroscience, Neuropsychopharmacology

Main Areas: Fizyoloji, 

2022 - The investigation of the effects of postnatal alcohol exposure on molecular content and antioxidant capacity of mice liver tissue
Algburi Ali Forat, DURSUN İLKNUR, GARİP USTAOĞLU ŞEBNEM. Elsevier BV, 310(),
2022 - The structural effects of Vitamin A deficiency on biological macromolecules due to ethanol consumption and withdrawal: An FTIR study with chemometrics
2017 - Effects of prenatal binge-like ethanol exposure and maternal stress on postnatal morphological development of hippocampal neurons in rats
Jakubowska Doğru Ewa,DURSUN İLKNUR,ELİBOL BİRSEN,YÜRÜKER ALİ CELALETTİN SİNAN. International Journal of Developmental Neuroscience, 61(), 40-50.
2014 - Examination of Age-dependent effects of fetal ethanol exposure on behavior, hippocampal cell counts, and doublecortin immunoreactivity in rats
DURSUN İLKNUR,ELİBOL BİRSEN,Jakubowska Doğru Ewa,Telkes İlknur,KILIÇ ERTUĞRUL,CANAN SİNAN. Developmental Neurobiology, 74(5), 498-513.
2013 - Effects of early postnatal alcohol exposure on the developing retinogeniculate projections in C57BL/6 mice
DURSUN İLKNUR,Jakubowska Doğru Ewa,van der List Deborah,ELİBOL BİRSEN,Chapman Barbara,Berman Robert F. Alcohol, 47(3), 173-179.
2011 - Effects of Early Postnatal Exposure to Ethanol on Retinal Ganglion Cell Morphology and Numbers of Neurons in the Dorsolateral Geniculate in Mice
DURSUN İLKNUR,Jakubowska Doğru Ewa,van der List Deborah,Liets Lauren C,Coombs Julie L,Berman Robert F. Alcoholism: Clinical and Experimental Research, 35(11), 2063-2074.
2006 - Effects of prenatal alcohol exposure on activity, anxiety, and memory in young adult Wistar rats
DURSUN İLKNUR,Jakubowska Doğru Ewa,UZBAY İSMAİL TAYFUN. Pharmacology, Biochemistry and Behavior, 85(2), 345-355.
Effects of prenatal alcohol exposure in young adult Wistar rats impact on activity, anxiety, and memory
2010 - İngilizce, Bilimsel Kitap
ISBN: 978-3-8383-7058-3
DURSUN İLKNUR,Jakubowska Doğru Ewa
"Wistar sıçanlarda nörogenezden sorumlu dentate girus bölgesindeki granül hücrelerinin yaşa bağlı morfolojik ve fizyolojik değişimleri", "Ulusal", "Sağlık Bilimleri Temel Alanı>Tıbbi Biyoloji",
"Insight into hippocampus development during the first two postnatal months in control and fetal alcohol rats", "Uluslararası", "Sağlık Bilimleri Temel Alanı->Tıbbi Biyoloji",
(2014), "NMDA receptor antagonism and prepulse inhibition test in behavioral models of schizophrenia", "Uluslararası", "Sağlık Bilimleri Temel Alanı->Sinirbilimi",
(2013), "Comparing postnatal development of the hippocampus in control and fetal-alcohol rats", "Uluslararası", "Sağlık Bilimleri Temel Alanı->Sinirbilimi",
(2013), "The effects of intracerebroventricular administration of STZ on insulin signaling pathway in rat brain", "Uluslararası", "Sağlık Bilimleri Temel Alanı->Sinirbilimi",
(2012), "Morphological Changes in Retina Ganglion Cells after Neonatal Ethanol Administration in Mice", "Uluslararası", "Sağlık Bilimleri Temel Alanı->Sinirbilimi",
(2010), "Investigation of Morphological Regeneration in The Neonatal Rat Hippocampus After Fetal Alcohol Administration", "Uluslararası", "Sağlık Bilimleri Temel Alanı->Sinirbilimi",
(2006), "Effects of chronic alcohol intake and withdrawal on memory and brain protein and lipid profiles assessed by FT– IR technique in young adult Wistar rats", "Uluslararası", "Sağlık Bilimleri Temel Alanı->Sinirbilimi",
(2005), "Effects of prenatal alcohol exposure on activity, anxiety and learning in young adult Wistar rats", "Uluslararası", "Sağlık Bilimleri Temel Alanı->Sinirbilimi",
(2009), "Confounding Factors, Gender and Age, in The Research of Fetal Ethanol Effects On Animal Behavior", "Uluslararası", "Sağlık Bilimleri Temel Alanı->Sinirbilimi",
(2009), "Effects of Postnatal Alcohol Exposure on Developing the Dorsal Lateral Genıculate Nucleus (dLGN) in the C57bl/6 Mice", "Uluslararası", "Sağlık Bilimleri Temel Alanı->Sinirbilimi",
(2006), "Effects of fetal alcohol on learning and memory are gender, age, and strain dependent", "Uluslararası", "Sağlık Bilimleri Temel Alanı->Sinirbilimi",
(2013), "Kontrol ve Fötal Alkole Maruz Kalmış Sıçanların Doğumdan Sonraki İlk İki Ayda Hippokampüs Gelişiminin İncelenmesi", "Ulusal", "Fen Bilimleri ve Matematik Temel Alanı->Biyoloji",