Faculty of Medicine

Academic Members

Prof. Tülin Tiraje Celkan

Prof.
Tülin Tiraje Celkan

Çocuk Hematolojisi ve Onkolojisi (Çocuk Sağlığı ve Hastalıkları)

MD Tülin Tiraje Celkan is 28 year expert in Pediatric Hematology-Oncology . Currently after 28 year in Istanbul University Cerrahpasa Medical Faculty, she is working in Vadi Liv Hospital and also İstinye University. She was graduated from Istanbul University Medical Faculty in 1986. She completed her residency in Anadolu University in Eskisehir in 1991. For obligatory service she was in Şanlıurfa and Viranşehir between 1991-1994. Finally she began her fellowship program at Cerrahpasa Faculty december 1994, appointed as associate professor in 2003, and professor in 2009. She visited Amsterdam Vu universty as a clinical observer in 1998. She was especially interested in different kind of bleeding and anemic patients and also leukemic and childdhood cancer patients. She has the largest patient cohort of plasminogen deficiency in the world. She has a large patient cohort of pediatric hemangiomas and AVM .

Araştırma Alanları

  • Pediatric Hematology and Oncological Diseases
  • especially childhood leukemia
  • Undiagnosed anemias
  • Undiagnosed bleeding disorders
  • Von Willebrand's disease
  • Plasminogen deficiency
  • Rare factor deficiencies
  • hemangiomas
  • Arterial and venous anomalies
  • Childhood solid tumors

Çalışma Alanları

  • Sağlık Bilimleri Temel Alanı
  • Çocuk Hematolojisi ve Onkolojisi (Çocuk Sağlığı ve Hastalıkları)
  • Medikolegal Değerlendirme Sürecine Yansıyan Çocukluk Çağı Aşı Uygulamaları, 2023
  • Telemedicine Applications in a Tertiary Pediatric Hospital in Turkey During COVID-19 Pandemic, 2021
  • Telemedicine Applications in a Tertiary Pediatric Hospital in Turkey During COVID-19 Pandemic, 2021
  • Safety of dabigatran etexilate for the secondary prevention of venous thromboembolism in children, 2020
  • Adrenal masses in children: Imaging, surgical treatment and outcome, 2020
  • Ligneous gingivitis: Hard to diagnose and treat, 2020
  • Comparison of outcomes of children with acute lymphoblastic leukemia treated with BMF protocol across 2 decades, 2020
  • Comparison of outcomes of children with acute lymphoblastic leukemia treated with BMF protocol across 2 decades, 2020
  • An Unusual Presentation of Carney Complex, 2020
  • PTEN and AKT1 Variations in Childhood T-cell Acute Lymphoblastic Leukemia, 2020
  • Use of hyperbaric oxygen therapy of purpura fulminans in an extremely low birth weight preterm: A case report, 2020
  • An usual presentation of Carney Complex, 2020
  • Cross-sectional study: long term follow-up care for pediatric cancer survivors in a developing country, Turkey: current status, challenges, and future perspectives, 2020
  • High TUBB2A expression in childhood T-ALL is correlated with the clinical outcome, 2020
  • Cross-sectional study: long term follow-up care for pediatric cancer survivors in a developing country, Turkey: current status, challenges, and future perspectives, 2020
  • OUTCOMES OF ELTROMBOPAG TREATMENT AND DEVELOPMENT OF IRON DEFICIENCY IN CHILDREN WITH IMMUNE THROMBOCYTOPENIA IN TURKEY, 2020
  • Adrenal masses in children: Imaging, surgical treatment and outcome, 2020
  • Ekstremite Yerleşimli Büyük Vasküler Anomaliler ve Seyri, 2020
  • Use of hyperbaric oxygen therapy of purpura fulminans in an extremely low birth weight preterm: A case report, 2020
  • Hemogram bize neler söyler?, 2020
  • High TUBB2A expression in childhood T-ALL is correlated with the clinical outcome, 2020
  • Adrenal masses in children: Imaging, surgical treatment and outcome, 2020
  • Comparison of outcomes of children with acute lymphoblastic leukemia treated with BMF protocol across 2 decades, 2020
  • Use of hyperbaric oxygen therapy of purpura fulminans in an extremely low birth weight preterm: A case report, 2020
  • Outcomes of eltrombopag treatment and development of iron deficiency in children with immune thrombocytopenia in Turkey İmmün trombositopenili çocuk hastalarda eltrombopag tedavisi ve tedaviye bağlı demir eksikliği, 2020
  • PTEN and AKT1 Variations in Childhood T-cell Acute Lymphoblastic Leukemia, 2020
  • Posterior Reversible Encephalopathy Syndrome in Childhood Hematological/Oncological Diseases, 2020
  • Posterior Reversible Encephalopathy Syndrome in Childhood Hematological/Oncological Diseases: Multicenter Results, 2020
  • Prognostic gene alterations and clonal changes in childhood B-ALL, 2019
  • Hepatosplenic Fungal Infections in Children With Leukemia. Risk Factors and Outcome: A Multicentric Study, 2019
  • Prognostic and clinical significance of expressions of P53, ERBB2, c-Kit and BCL2 in childhood medulloblastoma, 2019
  • Accidental High Dose Intrathecal Treatment - Late Result of A Patient, 2019
  • A novel combined treatment for plasminogen deficiency with lung involvement, 2019
  • Frequency of ALK and GD2 Expression in Neuroblastoma, 2019
  • Adrenal masses in children: Imaging, surgical treatment and outcome, 2019
  • PTEN and AKT1 Variations in Childhood T-cell Acute Lymphoblastic Leukemia, 2019
  • Homozygous c.130–131 ins A (pW44X) mutation in the HAX1 gene as the most common cause of congenital neutropenia in Turkey: Report from the Turkish Severe Congenital Neutropenia Registry, 2019
  • Posterior reversible encephalopathy syndrome in children with acute lymphoblastic leukemia: Experience of a single center using BFM protocols., 2019
  • Carney Complex: Unusual Presentation, 2019
  • Langerhans Cell Histiocytosis: Single Center Experience of 25 Years., 2019
  • Accidental High Dose Intrathecal Treatment - Late Result of A Patient, 2019
  • Ligneous gingivitis: Hard to diagnose and treat, 2019
  • A novel combined treatment for plasminogen deficiency with lung involvement, 2019
  • Pediatric Stroke, 2019
  • Carney Complex: Unusual Presentation, 2019
  • Congenital macrothrombocytopenia: is it misdiagnosed?, 2018
  • Coagulation Disturbances in Patients with Argininemia, 2018
  • Juvenile Myelomonocytic Leukemia in Turkey: A Retrospective Analysis of Sixty-five Patients, 2018
  • Sirolimus Experience in Blue Rubber Bleb Nevus Syndrome, 2018
  • Homozygous protein C deficiency presenting as neonatal purpura fulminans: management with fresh frozen plasma, low molecular weight heparin and protein C concentrate, 2018
  • Treatment of plasminogen deficiency patients with fresh frozen plasma., 2018
  • Association of the TLR4 and NOD2 Polymorphisms with Childhood Acute Lymphoblastic Leukemia, 2018
  • Use of a High-Purity Factor X Concentrate in Turkish Subjects with Hereditary Factor X Deficiency: Post Hoc Cohort Subanalysis of a Phase 3 Study, 2018
  • Thrombosis in children: which test to whom, when and how much necessary?, 2018
  • Coagulation Disturbances in Patients with Argininemia, 2018
  • Five year old girl with tongue bleeding, 2017
  • Juvenile Myelomonocytic Leukemia in Turkey: A Retrospective Analysis of 65 Patients, 2017
  • Plasminogen deficiency, 2017
  • The Association of TLR4 and NOD2 Polymorphisms with Childhood Acute Lymphoblastic Leukemia, 2017
  • ÇOCUKLUK ÇAĞI TÜMÖRLERİNİN AKCİĞER METASTAZLARINA CERRAHİ YAKLAŞIM, 2017
  • Wernicke s encephalopathy in a child with acute lymphoblastic leukemia, 2016
  • Novel plasminogen gene mutations in Turkish patients with type I plasminogen deficiency, 2016
  • Prenatal unilateral cerebellar hypoplasia diagnosed as PHACE syndrome, 2016
  • Pharmacokinetics of a high purity plasma derived factor X concentrate in subjects with moderate or severe hereditary factor X deficiency, 2016
  • Efficacy safety and pharmacokinetics of a new high purity factor X concentrate in subjects with hereditary factor X deficiency, 2016
  • Febrile neutropenia in children with acute lymphoblastic leukemia single center experience, 2016
  • Approach to the patient with neutropenia in childhood, 2015
  • A possible role for WNT5A hypermethylation in Pediatric Acute Lymphoblastic Leukemia, 2015
  • The difference between pre B cell acute lymphoblastic leukemia and Burkitt lymphoma in relation to DNA damage repair gene polymorphisms in childhood, 2015
  • Childhood mastocytosis results of a single center, 2015
  • The Role of Epstein Barr Virus LMP 1 Immunohistochemical Staining in Childhood Hodgkin Lymphoma, 2015
  • Deregulated WNT signaling in childhood T-cell acute lymphoblastic leukemia., 2014
  • Evaluation of Alpha Thalassemia Mutations in Cases with Hypochromic Microcytic Anemia The İstanbul Perspective, 2014
  • Deregulated WNT signaling in childhood T-cell acute lymphoblastic leukemia., 2014
  • A 17 year experience with ALL BFM protocol in acute lymphoblastic leukemia Prognostic predictors and interruptions during protocol, 2014
  • Novel use of propranolol for management of pain in children with vertebral hemangioma report of two cases, 2013
  • Coagulation factor activity and clinical bleeding severity in rare bleeding disorders results from the European Network of Rare Bleeding Disorders, 2012
  • DNA repair gene XPD and XRCC1 polymorphisms and the risk of febrile neutropenia and mucositis in children with leukemia and lymphoma, 2012
  • Cytopenia associated with iron deficiency anemia and iron therapy A report of two cases, 2011
  • Prognostic significance of NOTCH1 and FBXW7 mutations in pediatric T ALL, 2010
  • Late Effects of Childhood ALL Treatment on Body Mass Index and Serum Leptin Levels, 2010
  • Thiamine responsive megaloblastic anemia early diagnosis may be effective in preventing deafnes, 2009
  • Fatal Trichoderma harzianum infection in a leukemic pediatric patient, 2009
  • Malignancy associated hemophagocytic lymphohistiocytosis in pediatric cases a multicenter study from Turkey, 2009
  • DNA repair gene XPD and XRCC1 polymorphisms and the risk of childhood acute lymphoblastic leukemia, 2009
  • All-Trans Retinoic Acid, Interferon-α and Zoledronic Acid (Zometa) in the Treatment of a Patient with Resistant Metastatic Osteosarcoma, 2008
  • Syntaxin 11 is expressed in primary human monocytesmacrophages and acts as a negative regulator of macrophage engulfment of apoptotic cells and IgG opsonized target cells, 2008
  • Is Familial Mediterranean Fever a thrombotic disease or not, 2008
  • Defective cytotoxic lymphocyte degranulation in syntaxin 11 deficient familial hemophagocytic lymphohistiocytosis 4 FHL4 patients, 2007
  • CONTROL OF BLEEDING ASSOCIATED WITH HEMOPHAGOCYTIC SYNDROME IN CHILDREN An Audit of the Clinical use of Recombinant Activated Factor VII, 2007
  • Osseous presentation of Hodgkin s disease a case report and review of the literature, 2007
  • Sequencing of the factor 8 F8 coding regions in 10 Turkish hemophilia A patients reveals three novel pathological mutations and one rediagnosis of von Willebrand s disease type 2N, 2006
  • Retinoblastoma in Turkey survival and clinical characteristics 1981â 2004, 2006
  • THE ANEMIA OF FAMILIAL MEDITERRANEAN FEVER DISEASE, 2005
  • Prevalence of Anemia and the Risk Factors Among Schoolchildren in Istanbul, 2005
  • Antibody Titers and Immune Response to Diphtheria Tetanus Pertussis and Measles Mumps Rubella Vaccination in Children Treated for Acute Lymphoblastic Leukemia, 2005
  • NAD P H quinone oxidoreductase 1 null genotype is not associated with pediatric de novo acute leukemia, 2004
  • Blue Rubber Bleb Nevus Syndrome Associated with Consumption Coagulopathy Treatment with Interferon, 2004
  • Bacteremia in Childhood Cancer, 2002
  • Radiological features in paediatric primary gastric MALT lymphoma and association with Helicobacter pylori, 2002
  • Toxic Epidermal Necrolysis After the Use of High Dose Cytosine Arabinoside, 2001
  • Tropisetron Navoban R in the Control of Nausea and Vomiting Induced by Combined Cancer Chemotherapy in Children, 1999
  • Hemoglobin H Disease In Turkey Experience From Eight Center, 1900
  • IKZF1 Deletions at Diagnose and Relapse of Childhood B-ALL, 2017
  • Çocukluk Çağı B-All Hastalarında Tanı Ve Nüks Anındaki Moleküler Değişimlerin Dinamiği, 2017
  • Çocukluk Çağı B-All Gelişiminde Kanonik Olmayan Wnt Yolağı Prognoz ve Sağ Kalım İle İlişkili Olabilir, 2017
  • Çocukluk Çağı B-ALL Hastalarında IKZF1 Delesyonlarının Araştırılması, 2017
  • SLE’deki Hematolojik Değişikliklerin Hemofagositik Lenfohistiositoz İle İlişkisinin Araştırılması, 2019
  • T-akut lenfoblastik lösemi (T-ALL) Hastalarında Yüksek TUBB2A Gen Anlatımı ve siRNA Aracılı Modülasyonu, 2018
  • Determination of Zinc Finger Protein 384 (ZNF384) Gene Fusion in Childhood Acute Lymphoblastic Leukemia Patients, 2019
  • IKZF1 Deletions at Diagnose and Relapse of Childhood B-ALL, 2017
  • Akut Lösemili Hastalarda Zinc Finger Protein 384 (ZNF384) Geni Füzyonlarının Tespiti, 2019
  • Pharmacokinetic-guided prophylaxis based on bayesian model with myPKFiT (R) in hemophilia A: Turkish experience, 2019
  • Haemophilia A genotype-phenotype analysis in Turkey, 2019
  • Pharmacokinetic-guided prophylaxis based on bayesian model with my PKFİT in hemophilia A: Turkish experience, 2019
  • Akut Lösemili Hastalarda ’xx’xx Zinc Finger Protein 384’xx’xx (ZNF384) Geni Füzyonlarının Tespiti, 2019
  • Akut Lösemili Hastalarda ’xx’xx Zinc Finger Protein 384’xx’xx (ZNF384) Geni Füzyonlarının Tespiti, 2019
  • Akut Lösemili Hastalarda ’xx’xx Zinc Finger Protein 384’xx’xx (ZNF384) Geni Füzyonlarının Tespiti, 2019
  • Akut Lösemili Hastalarda ’xx’xx Zinc Finger Protein 384’xx’xx (ZNF384) Geni Füzyonlarının Tespiti, 2019
  • ÇOK MERKEZLİ DİAMOND-BLACKFAN ANEMİSİ MOLEKÜLER İNCELEME SONUÇLARI: EURODBA TÜRKİYE, 2019
  • Yenidoğanın nadir bir tümörü: özofagogastrik bölgeden kaynaklanan teratom.,
  • İşitme Engelli Okullarda Okuyan Makrotrombosit Saptanan Çocuklarda Myh-9 Gen Mutasyon Taraması, 2019
  • LONG-TERM RENAL OUTCOME IN PATIENTSWITH WILMS TUMOR, 2019
  • Akut Lösemili Hastalarda ’xx’xx Zinc Finger Protein 384’xx’xx (ZNF384) Geni Füzyonlarının Tespiti, 2019
  • Bilateral Wilms tümörü tedavi sonuçları çok merkezli çalışma, 2019
  • CENTRAL NERVOUS SYSTEM FUNGAL INFECTIONS IN CHILDREN WITH LEUKEMIA:RISK FACTORS AND OUTCOME: A MULTICENTRIC STUDY, 2018
  • Lösemi ve Kemik İliği Nakli Yapılan Olgularda Santral Sinir Sistemi Fungal Enfeksiyonla, 2018
  • DESMOID TYPE FIBROMATOSIS OF MANDIBLE: ACASE REPORT, 2018
  • Yenidoğanın nadir bir tümörü: özofagogastrik bölgeden kaynaklanan teratom, 2018
  • JUVENILE MYELOMONOCYTIC LEUKEMIA IN TURKEY: A RETROSPECTIVE ANALYSIS OF 65 PATIENT., 2017
  • PTEN AND AKT1 GENE VARIATIONS IN CHILDHOODT-ALL PATIENTS, 2017
  • Juvenile Myelomonocytic Leukemia in Turkey: A Retrospective Analysis of 65 Patient, 2017
  • Sürrenal kitlelere cerrahi yaklaşım: son 10 yılın değerlendirilmesi, 2017
  • HEPATIC VENOOCCLUSIVE DISEASE DURING TREATMENT OF ACUTE LYMPHOBLASTIC LEUKEMIA MANAGED WITH DEFIBROTIDE, 2016
  • PEDIATRIC VENOUS THROMBOEMBOLISM A SINGLE CENTRE EXPERIENCE, 2016
  • Hemophilia A single centre experience of 12 year, 2016
  • Langerhans Cell Histiocytosis Following Burkitt Lymphoma, 2016
  • Infection and Hemophagocytic Syndrome Single Center Experience, 2016
  • Pituitary Stalk Thickening and Diabetes Insipidus Proceeding to Langerhans Cell Histiocytosis, 2016
  • Hodgkin s Disease 1975 2012 Long Term Results of a Single Center, 2015
  • Surgical Interventions In Patients With Factor VII Deficiency, 2015
  • Intracranial Bleeding In Patients With Factor Deficiencies, 2015
  • CLINICAL MANIFESTATIONS AND TREATMENT OUTCOME OF FANCONI ANEMIA RESULTS OF A SINGLE CENTER, 2015
  • CHRONIC IMMUNE THROMBOCYTOPENIA IN CHILDHOOD EVALUATION OF THE DATA OVER 30 YEARS BASED ON THE REVISED CRITERIA OF INTERNATIONAL WORKING GROUP, 2015
  • LANGERHANS CELL HISTIOCYTOSIS ONE CENTER EXPERIENCE, 2015
  • MIFAMURTIDE L MTP PE IN CHILDREN WITH OSTEOSARCOMA THE TURKISH EXPERIENCE, 2015
  • OSTEONECROSIS A COMPLICATION OF TREATING CHILDHOOD CANCER A REPORT OF ZOLEDRONIC ACID THERAPY, 2015
  • TWO CASES OF SYSTEMIC TROMBOSIS AS A COMPLICATION OF INTRAARTERIAL CHEMOTHERAPY FOR RETINOBLASTOMA, 2015
  • çocuk hematolojionkolojide olgular, ISBN: 978-605-81045-3-2, 2019
  • hematolojide destek tedaviler, ISBN: 978-605-80353-6-2, 2020
  • çocuk hematolojide olgularla tromboz, ISBN: 978-505-06264-2-1, 2020
  • çocuk hematolojide olgularla tromboz, ISBN: 978-505-06264-2-1, 2020
  • Çocuk Hematolojide Olgularla tromboz, ISBN: 978-505-06264-2-1, 2020
  • çocuk hematolojide olgularla tromboz, ISBN: 978-505-06264-2-1, 2020
  • Kemik İliği Yetersizlikleri, ISBN: 978-605-7597-25-0, 2018
  • çocuk hematolojide olgularla tromboz, ISBN: 978-505-06264-2-1, 2020
  • çocuk hematolojide olgularla tromboz, ISBN: 978-505-06264-2-1, 2020
  • çocuk hematolojide olgularla tromboz, ISBN: 978-505-06264-2-1, 2020
  • Çocuk Hematoloji-Onkolojide Olgular, ISBN: 978-605-81045-3-2, 2019
  • çocuk hematoloji onkolojide olgular, ISBN: 978-605-81045-3-2, 2019
  • çocuk hematoloji onkolojide olgular, ISBN: 978-605-81045-3-2, 2019
  • çocuk hematoloji onkolojide olgular, ISBN: 978-605-81045-3-2, 2019
  • çocuk hematoloji onkoloji olgular, ISBN: 978-605-81045-3-2, 2019
  • çocuk hematoloji onkolojide olgular, ISBN: 978-605-81045-3-2, 2019
  • çocuk hematoloji onkolojide olgular, ISBN: 978-605-81045-3-2, 2019
  • çocuk hematoloji onkolojide olgular, ISBN: 978-605-81045-3-2, 2019
  • çocuk hematoloji-onkolojide olgular, ISBN: 978-605-81045-3-2, 2019
  • çocuk hematoloji onkolojide olgular, ISBN: 978-605-81045-3-2, 2019
  • çocuk hematoloji-onkolojide olgular, ISBN: 978-605-81045-3-2, 2019
  • çocuk hematoloji onkolojide olgular, ISBN: 978-605-81045-3-2, 2019
  • çocuk hematoloji-onkolojide olgular, ISBN: 978-605-81045-3-2, 2019
  • çocuk hematoloji onkolojide olgular, ISBN: 978-605-81045-3-2, 2019
  • çocuk hematoloji onkolojide olgular, ISBN: 978-605-81045-3-2, 2019
  • çocuk hematoloji-onkoloji olgular, ISBN: 978-605-81045-3-2, 2019
  • çocuk hematoloji-onkoloji, ISBN: 978-605-81045-3-2, 2019
  • çocuk hematoloji-onkoloji olgular, ISBN: 978-605-81045-3-2, 2019
  • çocuk hematoloji- onkoloji olgular, ISBN: 978-605-81045-3-2, 2019
  • ÇOCUK HEMATOLOİ-ONKOLOJİDE OLGULAR, ISBN: 978-605-81045-3-2, 2019
  • Çocuk Hematoloji Onkolojide Olgular, ISBN: 978-605-81045-3-2, 2019
  • Çocuk Hematoloji Onkolojide Olgular, ISBN: 978-605-81045-3-2, 2019
  • Çocuk Hematoloji Onkolojide Olgular, ISBN: 978-605-81405-3-2, 2019
  • Çocukluk Çağı Lösemilerinin Geç Komplikasyonları, ISBN: 2146-8740, 2018
  • pediatri, ISBN: 9978-975-277-666-1, 2017
  • pediatri, ISBN: 978-975-277-666-1, 2017
  • LÖSEMİLER, ISBN: , 2017
  • Pediatrinin Esasları, ISBN: , 2016
  • hematolog nadir hstalıklar, ISBN: , 2015
  • lenfoproliferatif hastalıklar serbest bildiri ödülü , 2007
  • ÇOCUKLUK ÇAĞINDA DEMİR EKSİKLİĞİNİN ÇİNKO İLE İLİŞKİSİNİN DEĞERLENDİRİLMESİ asistan tez yarışması , 2010
  • çocukluk çağı kronik miyolositer lösemi olgularının deerlendirilmesi türkiye verileri , 2015
  • THD klinik çalışma, 2017
  • Ülkemizde Pediatrik Hematoloji Kliniklerinde Tromboz: Çok Merkezli Çalışma Sonuçları”, 2018
  • en iyi sözlü sunum, 2020