Faculty of Medicine

Academic Members

Zeynep OCAK

Zeynep Ocak,  Prof.

Prof. Dr. Zeynep Ocak graduated from Atatürk University Faculty of Medicine in 2001. She completed her specialization education at the same university in 2007. Her Specialization Thesis was "Connexin 26 gene studies in non-syndromic hearing loss.". Between 2011 and 2014, Dr.Ocak worked as the Deputy Chief Physician of Abant İzzet Baysal University Faculty of Medicine Hospital and the head of the Genetic Diseases Diagnosis Center. Between 2013 and 2014, she worked at the Center for Genomic Medicine, Saitama Medical University in Japan, on diagnosis and treatment methods of mitochondrial diseases, molecular genetic techniques, and gene therapy. Dr. Ocak, who received the title of Associate Professor of Medical Genetics and Genetic Diseases in 2013, worked as the Director and responsible manager of the Genetic Diseases Diagnosis Center of Kanuni Sultan Süleyman Training and Research Hospital between 2014-2017. Between 2015-2016, she worked on HLA Tissue Typing, Flowcytometry and Transplantation at Dışkapı Yıldırım Beyazıt Training and Research Hospital Transplantation immunology, Tissue Typing and Transplantation Center. Between 2017-2019, she worked as a faculty member at Istanbul Yeni Yüzyıl University Faculty of Medicine Gaziosmanpaşa Hospital, Department of Medical Biology and Genetics and as the Head of the Genetic Diseases Diagnosis Center. Dr. Ocak, who received the Young Researcher Awards from the European Society of Human Genetics (ESHG) in 2009 in Vienna, Austria and in 2016 in Kyoto, Japan, has been involved in many multi-center studies in Japan, Europe and the USA. contributed to the elucidation of the genetic cause of many diseases. She has more than seventy articles published in international refereed journals and many book chapters. Research and interests; clinical genetics, cancer genetics, preimplantation genetic diagnosis, cell culture, microarray, SNParray, aCGH, NGS, epigenetics, sequencing, expression-based studies.

Research Areas: Genetics, Medical Genetics, Cancer

Main Areas: Tıbbi Genetik, 

Is There an Association Between Nasal Polyposis and ADAMTS Genes Expressions?
2021 - Uluslararası Hakemli
The Eurasian Journal of Medicine, YÜCE KAHRAMAN ÇİĞDEM, TATAR ARZU, KELEŞ MUZAFFER, OCAK ZEYNEP, TATAR ABDULGANİ
The Genomics of Arthrogryposis, a Complex Trait: Candidate Genes and Further Evidence for Oligogenic Inheritance
2019 - Uluslararası Hakemli
Elsevier BV, PEHLİVAN DAVUT, BAYRAM YAVUZ, GÜNEŞ NİLAY, Coban Akdemir Zeynep, Shukla Anju, Bierhals Tatjana, TABAKCI BURCU, ŞAHİN YAVUZ, GEZDİRİCİ ALPER, Fatih Jawid M, YILMAZ GÜLEÇ ELİF, YEŞİL SAYIN GÖZDE, Punetha Jaya, OCAK ZEYNEP, Grochowski Christopher M, KARACA ENDER, MUTLU ALBAYRAK HATİCE, Radhakrishnan Periyasamy, ERDEM HAKTAN BAĞIŞ, ŞAHİN İBRAHİM, YILDIRIM TİMUR, BAYHAN AVNİ İLHAN, Bursali Aysegul, ELMAS MUHSİN, YÜKSEL ZAFER, ÖZDEMİR ÖZTÜRK, SILAN FATMA, YILDIZ ONUR, YEŞİLBAŞ OSMAN, IŞIKAY SEDAT, BALTA BURHAN, Gu Shen, Jhangiani Shalini N, Doddapaneni Harsha, Hu Jianhong, Muzny Donna M, Boerwinkle Eric, Gibbs Richard A, Tsiakas Konstantinos, Hempel Maja, Girisha Katta Mohan, GÜL DAVUT, Posey Jennifer E, ELÇİOĞLU HURİYE NURSEL, TÜYSÜZ BEYHAN, Lupski James R
A Case of Sotos Syndrome with Congenital Sacrococcygeal Teratoma
2019 - Uluslararası Hakemli
Phoenix Journal, ALAY MUSTAFA TARIK, KALAYCI YİĞİN AYSEL, ÖZDEMİR FİLİZ, GÜMÜŞ UĞUR, OCAK ZEYNEP, SEVEN MEHMET
Toll-Like Receptor Gene Expression in Nasal Polyp
2016 - Uluslararası Hakemli
International Journal of Otolaryngology and Head & Neck Surgery, YURTTAŞ VEYSEL,APUHAN TAYFUN,ŞİMŞEK TUĞÇE,OCAK ZEYNEP,GÖK ÜZEYİR
Association of Toll like receptors 2 3 and 4 genes polymorphisms with periapical pathosis risk
2016 - Uluslararası Hakemli
Medicina Oral Patología Oral y Cirugia Bucal, ÖZAN ÜLKÜ,OCAK ZEYNEP,ÖZAN FATİH,OKTAY ELİF AYBALA,TOPTAŞ ORÇUN,ŞAHMAN HALİL,YIKILGAN İHSAN,ORUÇOĞLU HASAN,ER KÜRŞAT
Serum and aqueous xanthine oxidase levels, and mRNA expression in anterior lens epithelial cells in pseudoexfoliation
2015 - Uluslararası Hakemli
Graefe's Archive for Clinical and Experimental Ophthalmology, SİMAVLI HÜSEYİN,TOSUN MEHMET,BUCAK YASİN YÜCEL,ERDURMUŞ MESUT,OCAK ZEYNEP,ÖNDER HALİL İBRAHİM,ACAR MURADİYE
Clinical and cytogenetic results of a large series of amniocentesis cases from Turkey: Report of 6124 cases
2014 - Uluslararası Hakemli
JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH, OCAK ZEYNEP,Ozlu Tulay,YAZICIOĞLU HASAN FEHMİ,Ozyurt Osman Nuri,Aygün Mehmet
The effects of salidrosid on DIABLO and XAF1 gene expression in PC3 prostat cancer cells
2014 - Uluslararası Hakemli
Acta Medica Anatolia, ÜYETÜRK UĞUR,OCAK ZEYNEP,ACAR MURADİYE,ÖZBEY İSA,TEKELİOĞLU VİLDAN
The effects of hypericin on ADMTS and p53 gene expression in MCF 7 breast cancer cells
2014 - Uluslararası Hakemli
J BUON, acar muradiye,OCAK ZEYNEP,erdoğan kübra,çetin elif,HATİPOĞLU ÖMER FARUK,ÜYETÜRK ÜMMÜGÜL,gündüz esra,gündüz mehmet
Prenatal detection of Pai syndrome without cleft lip and palate: a case report.
2013 - Uluslararası Hakemli
GENETIC COUNSELING, YAZICIOĞLU HASAN FEHMİ,OCAK ZEYNEP
MOLECULAR CYTOGENETIC CHARACTERIZATION OF A CASE OF PRIMARY AMENORRHEA WITH INTRACHROMOSOMAL TRIPLICATION OF THE X CHROMOSOME Q ARM
2012 - Ulusal Hakemli
GENETIC COUNSELING, OCAK ZEYNEP
Walker-Warburg syndrome with persistent hyperplastic primary vitreous detected by prenatal ultrasonography
2010 - Uluslararası Hakemli
Ultrasound in Obstetrics and Gynecology, YAZICIOĞLU HASAN FEHMİ,OCAK ZEYNEP
Becker musküler distrofili geniş bir ailede moleküler ve klinik değerlendirme
2010 - Ulusal Hakemli
Zeynep Kamil Tıp Bülteni, TUĞ ESRA,ATASOY HALİL İBRAHİM,AYDIN HATİP,OCAK ZEYNEP
Primary Hypogonadism, Partial Alopecia, and Mullerian Hypoplasia: Report of a Third Family and Review
2009 - Ulusal Hakemli
AMERICAN JOURNAL OF MEDICAL GENETICS PART A, OCAK ZEYNEP
Osteogenezis İmperfecta Tanılı Çocukta Düşük Enerjili Kafa Travması Sonrasında Kranyum Fraktürü
2015 - Ulusal
Sağlık Bilimleri Temel Alanı->Acil Tıp ,
Role of Gene Variations of Toll like Receptors 2, 3 and 4on Genetic Susceptibility to Periapical Pathosis
2013 - Uluslararası
Sağlık Bilimleri Temel Alanı->DİŞ HEKİMLİĞİ ,
Analysis of HPV Incidence, Genotype and Age Distribution in aTraining and Research Hospital in Istanbul and Comparison of Results with Previous Literature from Turkey
2015 - Uluslararası
Sağlık Bilimleri Temel Alanı->Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji ,
Mozaik olmayan 49 XYYYY karyotipli bir vaka
2008 - Ulusal
Sağlık Bilimleri Temel Alanı->Kulak Burun Boğaz Hastalıkları ,
Hipogonadizm parsiyel alopezi ve mullerian hipoplazisi olan bir aile
2008 - Ulusal
Sağlık Bilimleri Temel Alanı->Kulak Burun Boğaz Hastalıkları ,
Familial t 2 5 in a Patient with micropenis
2007 - Uluslararası ISSN 0967-3849
Sağlık Bilimleri Temel Alanı->Kulak Burun Boğaz Hastalıkları ,
Nazal Polip Dokusunda IL 1A IL 10 ADAMTS 5 ADAMTS 8 ve ADAMTS 9 genlerinin expresyon analizleri
2014 - Uluslararası
Sağlık Bilimleri Temel Alanı->Kulak Burun Boğaz Hastalıkları ,