Faculty of Medicine

Academic Members

Ayca Zeynep İlter

Ayca Zeynep İlter,  Dr.

Faculty Member

Dr. Ayca Z. İlter completed her undergraduate education at Istanbul University, Biology Department in 2008. During her education, she also participated as an intern in several research projects at different institutions such as Charité University and Istanbul University Aziz Sancar Experimental Medicine Research Institute. She continued her postgraduate education at Yeditepe University Genetics and Bioengineering Department and graduated in 2011 with High Honors in Biotechnology. Ayca Z. İlter completed her PhD degree in Biotechnology at Yeditepe University in 2016. Her PhD thesis was titled “The effect of tissue transglutaminase induced integrin trafficking on kidney cancer metastasis”. Dr. İlter then became a postdoctoral fellow at Acıbadem University Medical School Microbiology Department. She worked on the epigenetic control of influenza virus-host interactions as a research scientist funded by The Scientific and Technological Research Council of Turkey (TUBİTAK) and served as principal investigator on scientific research project supported by Acıbadem University. Later, she was entitled to receive the TÜBİTAK BİDEB 2219 scholarship and worked at the University of Illinois (UIUC) Chemical and Biomolecular Engineering Department in the USA as visiting research fellow. She worked on a new chromatin-immunoprecipitation technique (CUT&RUN) to identify host-pathogen interactions and histone post-translational modifications by utilizing CRISPR-Cas9 techniques. Dr. Ayca İlter has expertise on many technical fields such as mammalian and bacterial cell culture, virus production, DNA-RNA-protein based molecular biology techniques, protein isolation and purification. Her research focus is on cellular immunotherapy, cancer biology and gene editing.

Main Areas: Histoloji ve Embriyoloji, 

2018 - Tissue transglutaminase expression is necessary for adhesion, metastatic potential and cancer stemness of renal cell carcinoma
Bagatur Yesim,AKÜLKE AYCA ZEYNEP,Bihorac Ajna,Erdem Merve,TELCİ DİLEK. CELL ADHESION MIGRATION, 12(2), 138-151.
2018 - Invertebrate Iridoviruses: A Glance over the Last Decade
İNCE İKBAL AGAH,Ozcan Orhan,AKÜLKE AYCA ZEYNEP,Scully Erin D.,Ozgen Arzu. VIRUSES-BASEL, 10(4),
2017 - Sambulin A and B, non-glycosidic iridoids from Sambucus ebulus, exert significant in vitro anti-inflammatory activity in LPS-induced RAW 264.7 macrophages via inhibition of MAPKs’xxs phosphorylation
ATAY BALKAN İREM,AKÜLKE AYCA ZEYNEP,Bagatur Yesim,TELCİ DİLEK,Goren Ahmet Ceyhan,KIRMIZIBEKMEZ HASAN,YEŞİLADA ERDEM. JOURNAL OF ETHNOPHARMACOLOGY, 206(null), 347-352.
2015 - Isolation of anti-inflammatory compounds from Sambucus ebulus leaves through in vitro activity-guided fractionation
ATAY BALKAN İREM,AKÜLKE AYCA ZEYNEP,Bağatur Yeşim,TELCİ DİLEK,KIRMIZIBEKMEZ HASAN,YEŞİLADA ERDEM. Planta Medica, 81(16),
2015 - Evaluation of in vitro anti-inflammatory effects of the remaining water subextract of Cistus laurifolius leaves
ATAY BALKAN İREM,AKÜLKE AYCA ZEYNEP,Bağatur Yeşim,TELCİ DİLEK,KIRMIZIBEKMEZ HASAN,YEŞİLADA ERDEM. Planta Medica, 81(16),
2012 - Importance of tissue transglutaminase on the activation of secretory phospholipase A2 in the oxidized LDL-treated vascular smooth muscle cells
AKÜLKE AYCA ZEYNEP,Griffin Martin,TELCİ DİLEK. FEBS Journal,
2011 - Effects of the extracts from Turkish medicinal plants on NF-κB activation on LPS-induced RAW 264.7 macrophages
ATAY BALKAN İREM,AKÜLKE AYCA ZEYNEP,TELCİ DİLEK,KIRMIZIBEKMEZ HASAN,YEŞİLADA ERDEM. Planta Medica, 77(12),
Stem Cells: Current Challenges and New Directions
2013 - İngilizce, Bilimsel Kitap
ISBN: 978-1-4614-8066-2
TELCİ DİLEK,AKÜLKE AYCA ZEYNEP,Erdem Merve