Faculty of Medicine

Faculty of Medicine

Academic Members

Siğnem Eyuboğlu

Siğnem Eyuboğlu,  Faculty Member, PhD

signem.eyuboglu@istinye.edu.tr
https://signemeyuboglu.com/
CV
Faculty Member

Asst. Prof. Siğnem Eyuboğlu graduated from Haliç University Molecular Biology and Genetics department in 2008 and got her master's degree in physiology from Kardeniz Technical University in 2013. She performed her PhD in experimental brain mapping and electrophysiology at Capa Medical Faculty, Istanbul University. She worked for ten years at Physiology Department Faculty of Medicine,Yeditepe University. Her major research interests are neuroendocrinology, neuroscience and cognitive behavior. She has experiences about optogenetics, chemogenetics and behavioral brain circuits. Dr. Eyuboglu joined the faculty of medicine at Istinye University in 2019.

Research Areas: Kisspeptin Nöronal Devreler ve Nöroanatomik Haritalama, Optogenetik ve Farmakogenetik manipülasyonlar, Bilişsel ve Davranışsal Sinirbilim, Öğrenme ve Hafıza Alzheimer Hastalığı, Endokrin Bozucular

Main Areas: Fizyoloji, 

2022 - Anti-Apoptotic Effects Of Valproic Acid Treatment On Dopaminergic Neuronal Loss In A 6-Hydroxydopamine Model Of Parkinson\u2019s Disease In Rats
CUMBUL ALEV, ÖZKARDEŞLER SİĞNEM, KELEŞ ELİF ÇİĞDEM, USLU ÜNAL, GENÇ MEHVEŞ ECE. Anadolu Kliniği Tıp Bilimleri Dergisi,
2021 - Polychlorinated biphenyls and organochlorine pesticides in breast milk samples and their correlation with dietary and reproductive factors in lactating mothers in Istanbul
AĞUŞ SAMİ, AKKAYA HATİCE, DAĞLIOĞLU NEBİLE, ÖZKARDEŞLER SİĞNEM, atasayan özge, METE FATİH, ÇOLAK CEMİL, SANDAL SÜLEYMAN, YILMAZ BAYRAM. Environmental Science and Pollution Research, 29(),
2019 - Comparison of the Effects of Dovitinib and Bevacizumab on Reducing Neovascularization in an Experimental Rat Corneal Neovascularization Model
Sahan Berna,çiftçi Ferda,EYUBOĞLU SİĞNEM,YABA UÇAR AYLİN,YILMAZ BAYRAM,Yalvaç Belkıs Ilgaz. Cornea, 1-.
2018 - Comparison of the neuroprotective effects of brimonidine tartrate and melatonin on retinal ganglion cells
Marangoz Deniz,Guzel Elif,EYUBOĞLU SİĞNEM,Gumusel Asli,Seckin Ismail,Ciftci Ferda,YILMAZ BAYRAM,Yalvac Ilgaz. International Ophthalmology, 38(6), 2553-2562.
2017 - Investigation of the effects of kisspeptin-10 in methionine-induced lipid peroxidation in testicle tissue of young rats
AKKAYA HATİCE,EYUBOĞLU SİĞNEM,ERKANLI ŞENTÜRK GÖZDE,YILMAZ BAYRAM. Journal of Biochemical and Molecular Toxicology, 31(5), 21881-.
2014 - Postacute Effects of Kisspeptin-10 on Neuronal Injury Induced by L-Methionine in Rats
AKKAYA HATİCE,KILIÇ ERTUĞRUL,EYUBOĞLU SİĞNEM,YILMAZ BAYRAM. Journal of Biochemical and Molecular Toxicology, 28(8), 373-377.
2014 - Promoter Methylation in Epithelial-Enriched and Epithelial-Depleted Cell Populations Isolated from Breast Milk
Browne Eva P,EYUBOĞLU SİĞNEM,Punska Elizabeth C,Agus Sami,Vitrinel Ayca,Erdag Gulay Ciler,Anderton Douglas L,Arcaro Kathleen F,YILMAZ BAYRAM. Journal of Human Lactation, 30(4), 450-457.
2013 - Leptin regulation of pubertal maturation in intact and pinealectomized female rats
KAÇAR EMİNE,EYUBOĞLU SİĞNEM,YILMAZ BAYRAM,KELEŞTİMUR HALUK. TURKISH JOURNAL OF MEDICAL SCIENCES, 43(), 557-561.
2011 - Effects of the gonadotropin-releasing hormone antagonist cetrorelix in the early postimplantation period on rat pregnancy
Tuğ Niyazi,USLU ÜNAL,CUMBUL ALEV,EYUBOĞLU SİĞNEM,Cam Cetin,Karateke Ates,YILMAZ BAYRAM. EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 155(2), 166-170.
HÜCRESEL TIP VE MEDİKAL BİYOTEKNOLOJİ UYGULAMALARI
2021 - Türkçe, Bilimsel Kitap ISBN: 978-625-7401-52-4
ÖZKARDEŞLER SİĞNEM
(2012), "Effects of kisspeptin-45 on neural lipid peroxidation in male rats", "Uluslararası", "Sağlık Bilimleri Temel Alanı->Fizyoloji",
(2013), "Promoter methylation in epithelial cells isolated frem breast milk of women from Istanbul, Turkey", "Uluslararası", "Sağlık Bilimleri Temel Alanı->Fizyoloji", "10.1158/1538-7445.AM2013-3646", "1538-7445",
(2015), "Effect of c-Abl gene silencing by siRNA on proliferation of Mouse granulosa cells", "Uluslararası", "Sağlık Bilimleri Temel Alanı->Fizyoloji", "10.1111/apha.12626",
(2018), "Chronic manuplation of arcuate kisspeptin neurons in AB1-42 induced mouse model of Alzheimer’xxs disease", "Uluslararası", "Sağlık Bilimleri Temel Alanı->Fizyoloji",
(2015), "Investigation of effects of kisspeptin10 in methionine induced lipid peroxidation in testis tissue of young male rats.", "Uluslararası", "Sağlık Bilimleri Temel Alanı->Fizyoloji", "10.1111/apha.12626",
(2015), "Investigation of epigenetic changes in exfoliated mammary epithelial cells retrieved from lactating women", "Uluslararası", "Sağlık Bilimleri Temel Alanı->Fizyoloji", "10.1111/apha.12626",
(2013), "Effects of chronic infusion of kisspeptin and its antagonist on cognitive functions and behavior in female rats", "Uluslararası", "Sağlık Bilimleri Temel Alanı->Fizyoloji",
(2015), "Midkine, TNF-a and cytochrome C expressions in kainic acid induced epileptic seizures in rats.", "Uluslararası", "Sağlık Bilimleri Temel Alanı->Fizyoloji", "10.1111/apha.12626",
(2014), "Comparison of exfoliated human mammary cells count with demographical and nutrional parameters of lactating mothers", "Uluslararası", "Sağlık Bilimleri Temel Alanı->Fizyoloji", "10.1111/apha.12362",