Faculty of Medicine

Academic Members

Asst. Prof. Siğnem Eyuboğlu graduated from Haliç University Molecular Biology and Genetics department in 2008 and got her master's degree in physiology from Kardeniz Technical University in 2013. She performed her PhD in experimental brain mapping and electrophysiology at Capa Medical Faculty, Istanbul University. She worked for ten years at Physiology Department Faculty of Medicine,Yeditepe University. Her major research interests are neuroendocrinology, neuroscience and cognitive behavior. She has experiences about optogenetics, chemogenetics and behavioral brain circuits. Dr. Eyuboglu joined the faculty of medicine at Istinye University in 2019.

Research Areas: Kisspeptin nöronal devreler ve nöroanatomik haritalama, Optogenetik ve Farmakogenetik manipülasyonlar, Bilişsel ve davranışsal sinirbilim, Öğrenme ve hafıza, Alzheimer Hastalığı, Elektronörofizyoloji , Endokrin bozucular

Main Areas: Fizyoloji, 

2019 - Comparison of the Effects of Dovitinib and Bevacizumab on Reducing Neovascularization in an Experimental Rat Corneal Neovascularization Model
Sahan Berna,çiftçi Ferda,EYUBOĞLU SİĞNEM,YABA UÇAR AYLİN,YILMAZ BAYRAM,Yalvaç Belkıs Ilgaz. Cornea, 1-.
2018 - Comparison of the neuroprotective effects of brimonidine tartrate and melatonin on retinal ganglion cells
Marangoz Deniz,Guzel Elif,EYUBOĞLU SİĞNEM,Gumusel Asli,Seckin Ismail,Ciftci Ferda,YILMAZ BAYRAM,Yalvac Ilgaz. International Ophthalmology, 38(6), 2553-2562.
2017 - Investigation of the effects of kisspeptin-10 in methionine-induced lipid peroxidation in testicle tissue of young rats
AKKAYA HATİCE,EYUBOĞLU SİĞNEM,ERKANLI ŞENTÜRK GÖZDE,YILMAZ BAYRAM. Journal of Biochemical and Molecular Toxicology, 31(5), 21881-.
2014 - Postacute Effects of Kisspeptin-10 on Neuronal Injury Induced by L-Methionine in Rats
AKKAYA HATİCE,KILIÇ ERTUĞRUL,EYUBOĞLU SİĞNEM,YILMAZ BAYRAM. Journal of Biochemical and Molecular Toxicology, 28(8), 373-377.
2014 - Promoter Methylation in Epithelial-Enriched and Epithelial-Depleted Cell Populations Isolated from Breast Milk
Browne Eva P,EYUBOĞLU SİĞNEM,Punska Elizabeth C,Agus Sami,Vitrinel Ayca,Erdag Gulay Ciler,Anderton Douglas L,Arcaro Kathleen F,YILMAZ BAYRAM. Journal of Human Lactation, 30(4), 450-457.
2013 - Leptin regulation of pubertal maturation in intact and pinealectomized female rats
KAÇAR EMİNE,EYUBOĞLU SİĞNEM,YILMAZ BAYRAM,KELEŞTİMUR HALUK. TURKISH JOURNAL OF MEDICAL SCIENCES, 43(), 557-561.
2011 - Effects of the gonadotropin-releasing hormone antagonist cetrorelix in the early postimplantation period on rat pregnancy
Tuğ Niyazi,USLU ÜNAL,CUMBUL ALEV,EYUBOĞLU SİĞNEM,Cam Cetin,Karateke Ates,YILMAZ BAYRAM. EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 155(2), 166-170.