Tıp Fakültesi

Tıp Fakültesi

Akademik Kadro

Ferda Kaleağasıoğlu

Ferda Kaleağasıoğlu,  Prof. Dr.

ferda.kaleagasioglu@istinye.edu.tr
https://medicine.istinye.edu.tr/tr/kadro/5853
CV
Öğretim Üyesi

Prof. Dr. Ferda Kaleağasıoğlu 1978 yılında Kadiköy Anadolu Lisesinden ve 1984 yılında İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesinden mezun oldu. 1984-1986 yılları arasında Alanya Verem Savaş Dispanseri’nde mecburi hizmetini yaptı. 1986-1991 yılları arasında Cerrahpaşa Tıp Fakültesinde Tıbbi Farmakoloji uzmanlığı eğitimini tamamladı. 1989 yılından itibaren Alman Kanser Araştırma Merkezinde/Almanya yürütülen projelere katıldı.1991-1996 yılları arasında, İ.Ü. Onkoloji Enstitüsü ve İ.Ü. Aziz Sancar Deneysel Tıp Araştırma Enstitüsünde ve 1996’ da ise ilaç endüstrisine geçerek, çok uluslu ilaç firmalarında Bilimsel Proje Yöneticisi, Ülke Ar-Ge Müdürü, Medikal ve Ruhsat Departmanları Yöneticisi, Firma Basın Sözcüsü, Endüstriyel İlişkiler Müdürü, Yönetim Kurulu Üyesi, ve Avrupa-Orta Doğu-Asya Klinik Çalışmalar Kurulu üyesi olarak çalıştı. 2011’den itibaren yeniden akademisyenliğe dönerek Yeditepe Üniversitesi Mühendislik Fakültesi Genetik ve Biyoteknoloji Anabilim Dalında (2011-2012), Yakın Doğu Tıp Fakültesi Tıbbi Farmakoloji Anabilim Dalında (2012-2014; 2017-2020) ve Yeditepe Üniversitesi Tıp Fakültesi (2014-2017) Tıbbi Farmakoloji Anabilim Dalında görev yaptı. Akademik çalışmalarının yanısıra, Dönem Koordinatörü, Araştırma Eğitimini Geliştirme Komitesi üyesi, Araştırma Stratejileri Komitesi üyesi, Etik Kurul üyesi ve Öz Değerlendirme Koordinatörü gibi pek çok idari görevde bulundu. Bilimsel ilgi alanları kanser, nörodejeneratif hastalıklar ve bilinçtir.

Araştırma Alanları: Kanser Farmakolojisi, Moleküler Farmakoloji

Temel Alanları: Tıbbi Farmakoloji, 

2021 - Dual Akt and Bcl-2 inhibition induces cell-type specific modulation of apoptotic and autophagic signaling in castration resistant prostate cancer cell lines
AVŞAR ABDİK EZGİ, ABDİK HÜSEYİN, TURAN DUYGU, ŞAHİN FİKRETTİN, Berger Martin. Molecular Biology Reports,
2020 - Multiple Facets of Autophagy and the Emerging Role of Alkylphosphocholines as Autophagy Modulators
KALEAĞASIOĞLU SABİRE FERDA,ALI DOAA A,BERGER MARTIN R. Frontiers in Pharmacology, 11(), 547-.
2019 - ABT-737 and erufosine combination against castration-resistant prostate cancer: a promising but cell-type specific response associated with the modulation of anti-apoptotic signaling
AVŞAR ABDİK EZGİ,KALEAĞASIOĞLU SABİRE FERDA,ABDİK HÜSEYİN,ŞAHİN FİKRETTİN,BERGER MARTIN R. ANTI-CANCER DRUGS, 30(4), 383-393.
2019 - Alkylphospholipids are signal transduction modulators with potential for anticancer therapy
KALEAĞASIOĞLU SABİRE FERDA,ZAHARIEVA MAYA M,KONSTANTINOV SPIRO M,BERGER MARTIN R. Anti-Cancer Agents in Medicinal Chemistry, 19(1), 66-91.
2018 - Analysis of Heart Rate variability (HRV) in Frequency Domain and Recurrence Quantification Analysis during the Treatment by Transcutaneous Vagus Nerve Stimulation
Conte Sergio,Wang Fang,Altamura Mario,Bellomo Antonello,Serafini Giuseppe,Orsucci Franco,KALEAĞASIOĞLU SABİRE FERDA,Mendolicchio Leonardo,Casciaro Francesco,Norman Rich,Conte Elio. Annals of Depression and Anxiety, 5(1), 1093-.
2018 - Multifractal Analysis of Heart Rate Variability in Subjects Affected from Dysfunction of Autonomic Nervous System in Anxiety and Depression and Treated by Transcutaneous Vagus Nerve Stimulation
Conte Sergio,Wang Fang,Sala Nicoletta,Casciaro Francesco,Serafini Giuseppe,KALEAĞASIOĞLU SABİRE FERDA,Norman Rich,Conte Elio. Austin Cardiology, 3(1), 1016-.
2018 - Measurements of Electroencephalogram(EEG),Galvanic Skin Resistance(GSR) and Heart Rate Variability(HRV) during the Application of a System that gives simultaneously tVNS and Brain Entrainment on Subjects Affected by Depression and Anxiety.
Casciaro Francesco,Conte Sergio,Altamura Mario,Bellomo Antonello,Serafini Giuseppe,Orsucci Franco,KALEAĞASIOĞLU SABİRE FERDA,Mendolicchio Leonardo,Norman Rich,Conte Elio. Annals of Depression and Anxiety, 5(2), 1095-.
2018 - Statins as potential agents for the prevention and treatment of osteoporosis
KALEAĞASIOĞLU SABİRE FERDA,ERCAN OLCAY,ONUR EMİN RÜŞTÜ. ENDOCRINE, 62(1), 269-269.
2017 - Isolation rates and antibiotic susceptibilities of different species belonging to Enterobacteriaceae family as urinary tract infection agents in Turkey: Systematic Review
YÜRÜYEN CANER, GÜROL YEŞİM, ÇELİK GÜLDEN, KALEAĞASIOĞLU SABİRE FERDA, ALTUNOK ELİF ÇİĞDEM. Turkish Journal Of Medical Sciences,
2017 - Rorschach ink-blots are multifractals and a corresponding multifractal strucure is realized in humans during their perception as measured by the GSR (galvanic skin response) neurological and psycho-pysiological signal.
CONTE SERGIO,Mendolicchio Leonardo,KALEAĞASIOĞLU SABİRE FERDA,Norman Rich,Wang Fang,Casciaro Francesco,LOSITO ANNA MARIA,CONTE ELIO,Orsucci Franco. Chaos and Complexity Letters, 10(3), 187-210.
2017 - The quantum statistical mechanics in the analysis of the context dependence in quantum cognition studies: may a quantum statistical analysis connect the science of complexity?
CONTE ELIO,KALEAĞASIOĞLU SABİRE FERDA,NORMAN RICH. Chaos and Complexity Letters, 11(2), 203-218.
2017 - The transcutaneous vagus nerve stimulation output of the nucalm device of solace lifesciences is found to be a multifractal and therefore it is indicated in the treatment of heart rate variability in the dysfunction of autonomic nervous system in anxiety, depression and stress
Conte Sergio,Wang Fang,Sala Nicoletta,Casciaro Francesco,Orsucci Franco,Serafini Giuseppe,KALEAĞASIOĞLU SABİRE FERDA,Mendolicchio Leonardo,Norman Rich,CONTE ELIO. Journal of Behavioral and Brain Science, 7(11), 532-543.
2017 - Amiyotrofik lateral skleroz: Güncel yaklaşım ve farmakoterapi.
KALEAĞASIOĞLU SABİRE FERDA. Türkiye Klinikleri Farmakoloji Özel Konular, 5(1), 34-42.
2017 - The Transcutaneous Vagus Nerve Stimulation Device of the Nu-Calm-Solace Lifesciences Gives an Output Signal that is a Multifractal: Is there a Support in the Treatment of the Atrial Fibrillation?
Conte Sergio,Sala Nicoletta,Wang Fang,Serafini Giuseppe,KALEAĞASIOĞLU SABİRE FERDA,Mendolicchio Leonardo,Casciaro Francesco,Orsucci Franco,Norman Rich,Pierfelice OO,Conte Elio. Austin Cardiology, 2(2), 1013-.
2017 - Statin-induced calcific Achilles tendinopathy in rats: comparison of biomechanical and histopathological effects of simvastatin, atorvastatin and rosuvastatin
KALEAĞASIOĞLU SABİRE FERDA,Olcay Ercan,OLGAÇ NECAT VAKUR. Knee Surgery, Sports Traumatology, Arthroscopy, 25(6), 1884-1891.
2014 - Alkylphosphocholines and the current anticancer profile of erufosine
Berger Martin. International journal of molecular medicine, 34(1), 34-.
2014 - Differential effects of erufosine on proliferation, wound healing and apoptosis in colorectal cancer cell lines
KALEAĞASIOĞLU SABİRE FERDA,BERGER MARTIN R. ONCOLOGY REPORTS, 31(3), 1407-1416.
2014 - SIBLING and SPARC Families: Their emerging roles in pancreatic cancer
KALEAĞASIOĞLU SABİRE FERDA,BERGER MARTIN R. WORLD JOURNAL OF GASTROENTEROLOGY, 20(40), 14747-14759.
2013 - A quantum mechanical interpretation of metacognition
KALEAĞASIOĞLU SABİRE FERDA,ONUR EMİN RÜŞTÜ. International Journal of Research and Reviews in Applied Sciences, 16(4), 93-100.
2012 - Fluoroquinolone induced tendinopathy: Etiology and Preventive Measures
KALEAĞASIOĞLU SABİRE FERDA,ERCAN OLCAY. TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE, 226(6), 251-258.
2012 - Conte’s Approach to human cognition by application of quantum mechanics: a revisitation of the Yin-Yang theory and Jung’s psyche model by using such quantum approach
KALEAĞASIOĞLU SABİRE FERDA. NeuroQuantology, 10(4), 655-662.
2011 - Oral toxicity of pefloxacin, norfloxacin, ofloxacin and ciprofloxacin: Comparison of biomechanical and histopathological effects on Achilles tendon in rats.
ERCAN OLCAY,BEYTEMUR OZAN,KALEAĞASIOĞLU SABİRE FERDA,GÜLMEZ TURGUT,MUTLU ZİHNİ,OLGAÇ NECAT VAKUR. JOURNAL OF TOXICOLOGICAL SCIENCES, 36(3), 339-345.
1995 - Research on Cistus Laurifolius L: Cytotoxicity and lethal toxicity.
KALEAĞASIOĞLU SABİRE FERDA,ÜNLÜ VESİLE SELMA,AYTUĞ BURHAN,BİLGE NİJAD,MERİÇLİ ALİ HİKMET,GÜVEN KASIM CEMAL. Acta Pharmaceutica Turcica (Continued by, Acta PharmaceuticaSciencia), 36(1), 25-28.
1995 - Acute oral toxicity of 3,7-bis-(4-trifluoromethylphenyl)-1,5,3,7-dioxadiazocane in rat compared with 3,7-bis-(3- trifluoromethylphenyl)-1,5,3,7-dioxadiazocane and N,N’-oxydimethylene bis -(2-trifluoromethylaniline).
KALEAĞASIOĞLU SABİRE FERDA,BERGER MARTIN R,KOLAR GEORGE F. TOXICOLOGY, 97(1-3), 123-131.
1995 - Cytostatic activity of marine algae
ÜNLÜ VESİLE SELMA,KALEAĞASIOĞLU SABİRE FERDA,BİLGE NİJAD,GÜVEN KASIM CEMAL. PHARMAZIE, 50(5), 369-370.
1994 - A study on cytotoxicity of Cichorium Endivia L.
KALEAĞASIOĞLU SABİRE FERDA,ÜNLÜ VESİLE SELMA,GÖNEN AYŞEGÜL,BİLGE NİJAD,GÜVEN KASIM CEMAL. Acta Pharmaceutica Turcica (Continued by, Acta PharmaceuticaSciencia), 36(2), 33-37.
1994 - Cytotoxic activity of rosa canina L. fructus
KALEAĞASIOĞLU SABİRE FERDA,ÜNLÜ VESİLE SELMA,BİLGE NİJAD,GÜVEN KASIM CEMAL. Acta Pharmaceutica Sciencia, 36(2), 59-63.
1994 - Chemosensitivity of human breast carcinoma cell lines to 1 - (2-chloroethyl)-1-nitroso-3-(2-hydroxyethyl)urea linked to acetobisdesmethyltamoxifen, estradiol and dihydrotestosteron.
KALEAĞASIOĞLU SABİRE FERDA,BERGER MARTIN R,SCHMAEL DIETRICH,EISENBRAND GERHARD. Turkish Journal Of Medical Sciences, 21(), 231-234.
1994 - Does retinoic acid inhibit or stimulate proliferation?
KALEAĞASIOĞLU SABİRE FERDA,BERGER MARTIN R. Turkish Journal Of Medical Sciences, 22(), 217-221.
1993 - Antiproliferative effect of retinoic acid and some novel derivatives in breast and colorectal cancer cell lines of human origin
KALEAĞASIOĞLU SABİRE FERDA,BERGER MARTIN R,GIESEL DOEPNER,BIESALSKI HANS KONRAD. Arzneimittel-Forschung (Drug Research), 43(4), 487-490.
1992 - Cytotoxic activity of a new hydroxyanthraquinone derivative compared with that of mitoxantrone.
KALEAĞASIOĞLU SABİRE FERDA,BAYKUT FİKRET. Acta Pharmaceutica Turcica (Continued by, Acta Pharmaceutica Sciencia)., 34(3), 75-79.
1992 - Identification of antineoplastic agents by thin layer chromatography.
KALEAĞASIOĞLU SABİRE FERDA. Acta Pharmaceutica Turcica (Continued by, Acta PharmaceuticaSciencia), 34(4), 115-119.
1990 - Mutagenic and genotoxic effects of extracts derived from edible mushroom Agaricus bisporus
POOL ZOBEL PL,PETER SCHMEZER,SINCHRANATANT YY,KALEAĞASIOĞLU SABİRE FERDA,REINHART KONRAD,MARTIN ROGER,KLEIN PETER,TRICKER AR. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 116(), 475-479.
1990 - Cancer incidence rates in Turkey and two regions in the Federal Republic of Germany
KALEAĞASIOĞLU SABİRE FERDA,BERGER MARTIN R,SCHMAEL DIETRICH. Archiv für Geschwulstforschung, 60(3), 201-208.
1990 - In vitro evaluation of 1-(2-chloroethyl)-1-nitroso-3-(2-hydroxyethyl)urea linked to 4-acetoxy-bisdesmethyltamoxifen, estradiol and dihydrotestosterone.
KALEAĞASIOĞLU SABİRE FERDA,BERGER MARTIN R,SCHMAEL DIETRICH,EISENBRAND GERHARD. Arzneimittel-Forschung (Drug Research), 40(5), 603-606.
Algebraic Quantum Theory of Consciousness (A Bare Bone Skeleton of Quantum Mechanics)
2018 - İngilizce, Bilimsel Kitap ISBN: 978-88-255-1707-1
CONTE ELIO,KALEAĞASIOĞLU SABİRE FERDA
İlaç İndeksi 2012
2012 - Türkçe, Bilimsel Kitap ISBN: 978-975-420-898-6
GÜVEN KASIM CEMAL,KALEAĞASIOĞLU SABİRE FERDA,KIROĞLU HAYRİYE
Natural Products (Alkaloids of Marine Macroalgae)
2013 - İngilizce, Bilimsel Kitap ISBN: 978-3-642-22143-9
GÜVEN KASIM CEMAL,ÇOBAN MUSTAFA BURAK,SEZİK EKREM,ERDUGAN HÜSEYİN,KALEAĞASIOĞLU SABİRE FERDA
Natural Products (Pharmacology of Macroalgae Alkaloids)
2013 - İngilizce, Bilimsel Kitap ISBN: 978-3-642-22144-6
KALEAĞASIOĞLU SABİRE FERDA,GÜVEN KASIM CEMAL,SEZİK EKREM,ERDUGAN HÜSEYİN,ÇOBAN MUSTAFA BURAK
Natural Products (Volatile Oils in Marine Macroalgae)
2013 - İngilizce, Bilimsel Kitap ISBN: 978-3-642-22144-6
GÜVEN KASIM CEMAL,SEZİK EKREM,KALEAĞASIOĞLU SABİRE FERDA,ERDUGAN HÜSEYİN,ÇOBAN MUSTAFA BURAK,KARAKAŞ ELİF